INIA: Informatics Core

INIA：信息学核心

• 批准号: 6694077
• 负责人: JAY R SNODDY
• 金额: $ 30.56万
• 依托单位: UNIVERSITY OF TENNESSEE KNOXVILLE
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-01-01 至 2006-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6694077
• 关键词: Internet; alcoholism /alcohol abuse; biomedical facility; computer data analysis; computer system design /evaluation; cooperative study; data collection methodology /evaluation; data management; informatics; information dissemination; information systems; statistics /biometry; technology /technique development

DESCRIPTION (provided by applicant): The Informatics Core of the Integrative Neurosciences Initiative on Alcoholism (INIA) provides central informational and computational resources for the different INIA research projects and cores. This INIA informatics core will, first, provide the collaborative information management, information technologies, and databases that are critical for these INIA projects to acquire and manage their data. The informatics core will develop a number of collaborative information systems that should help break down the geographic barriers to scientific collaboration; this core will enable the evaluation and direct application of these information-technology-backed collaborative tools for use by MA researchers. For exploratory research, several electronic laboratory notebooks will be developed. In addition, web-accessible lab information systems will also be built for larger-scale data discovery projects that allow central tracking and sharing of very different kinds of phenotype data about the same mouse strain from different research labs and institutions. Secondly, this core will provide some computational analysis and data mining tools that should enable INIA researchers to sift through their data for interesting patterns, especially patterns that might suggest hypotheses that can be tested by further experiments. In addition, the core will help initiate and foster collaborations between experimental INIA researchers and other computational researchers that might not be directly funded by this project. Thirdly, this core needs to make the finished INIA information freely available to the entire community via database-backed web sites and promote interperability of its data with data from other projects. For the subset of data that a community database can accept, the informatics core will need to package and forward that data to them. This core will work with other informatics researchers and developers on common data schemas, domain ontologies, data formats, and other ways to promote interperability across different data and databases.

描述（由申请人提供）： 关于酒精中毒综合神经科学倡议的信息核心 （Inia）为中央信息和计算资源提供 不同的INIA研究项目和核心。这个Inia Informatics Core将会， 首先，提供协作信息管理，信息 对于这些INIA项目至关重要的技术和数据库 获取并管理他们的数据。信息学核心将发展多个 应有助于分解地理的协作信息系统 科学合作的障碍；该核心将使评估能够 这些信息技术支持的协作工具的直接应用 用于MA研究人员的使用。对于探索性研究，几个电子 将开发实验室笔记本。此外，Web访问实验室 信息系统还将用于大规模数据发现 允许中央跟踪和共享非常不同种类的项目 关于来自不同研究实验室的相同小鼠菌株的表型数据和 机构。其次，该核心将提供一些计算分析，并且 数据挖掘工具应使INIA研究人员能够筛选其 有趣的模式的数据，尤其是可能暗示的模式 可以通过进一步实验来检验的假设。另外，核心 将有助于启动和促进实验INIA之间的合作 研究人员和其他可能不是直接的计算研究人员 由这个项目资助。第三，这个核心需要使成品INIA 通过数据库支持的网络免费提供给整个社区的信息 网站并通过来自其他项目的数据来促进其数据的可互置性。 对于社区数据库可以接受的数据子集，信息学 核心将需要包装并将这些数据转发给他们。这个核心将起作用 与其他信息学研究人员和开发人员有关常见数据模式的开发人员， 领域本体论，数据格式和其他促进可互操作性的方法 跨不同的数据和数据库。