The Neural Correlates of Encoding Specificity

编码特异性的神经相关性

• 批准号: 6659023
• 负责人: ALISON R PRESTON
• 金额: $ 2.25万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-17 至 2003-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6659023
• 关键词: functional magnetic resonance imaging; human subject; memory; neural information processing; neuroanatomy; predoctoral investigator

DESCRIPTION (provided by applicant): A fundamental principle of human memory known as encoding specificity states that the way in which an event is experienced determines how memory for that event is stored and later retrieved. In terms of neural systems, encoding specificity predicts that brain regions active during encoding will be re-activated during episodic retrieval reflecting the recapitulation of an original experience as it is remembered. A second principle of human memory know as transfer appropriate processing states that memory performance is facilitated when the same processing is evoked at both encoding and retrieval. In terms of neural systems, this principle would predict that re-activation of encoding specific brain regions during episodic retrieval will be greater when encoding and retrieval processing is matched relative to when processing is mismatched. The aim of this proposal is find evidence for encoding-specific re-activation during episodic retrieval and to test the predictions made by each of these principles using event-related fMRI. In addition, we will investigate how the phenomenon of encoding-specific reactivation is related to successful episodic memory retrieval.

描述（由申请人提供）：人类记忆的基本原则 被称为编码特异性指出事件的方式 经验丰富的确定该事件的内存是如何存储的并后来检索的。 在神经系统方面，编码特异性预测大脑区域 编码期间的活动将在情节检索期间重新激活 反映了人们记得的原始体验的概括。一个 人类记忆的第二个原则称为转移适当的处理状态 当唤起相同处理时，可促进内存性能 编码和检索。就神经系统而言，该原则将 预测情节过程中编码特定大脑区域的重新激活 匹配编码和检索处理时，检索将更大 相对于处理不匹配的处理。该提议的目的是找到 在情节检索过程中进行编码特定重新激活的证据 使用与事件相关的fMRI测试这些原理中的每一个的预测。 此外，我们将研究如何编码特定的现象 重新激活与成功的情节记忆检索有关。