DATA COLLECT: HEAVY ATOM DERIVATIVES OF EPSTEIN BARR VIRUS NUCLEAR ANTIGEN 1

数据收集：爱泼斯坦巴尔病毒核抗原 1 的重原子衍生物

• 批准号: 6437462
• 负责人: ALED M EDWARDS
• 金额: $ 14.32万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-03-01 至 2002-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6437462
• 关键词: bioimaging /biomedical imaging; biomaterials; biomedical resource; proteins; radiography; structural biology

The Epstein Barr Virus Nuclear Antigen-1 (EBNA1) orchestrates the initiation of DNA replication from the latent origin of this virus. EBNA1 belongs to a class of proteins that have not been probed by high resolution structural techniques. We have high quality crystals that are amenable to X-ray diffraction studies. The solution to this structure will allow for a molecular understanding of the events leading up to cell division in eukaryotes.

Epstein Barr 病毒核抗原 1 (EBNA1) 协调 DNA复制从该病毒的潜在起源开始。 EBNA1属于一类尚未被高水平探测的蛋白质。 分辨率结构技术。 我们拥有高品质的晶体 适合 X 射线衍射研究。 解决这个问题的办法 结构将允许对事件进行分子理解 导致真核生物的细胞分裂。