Cognitive Aging and Everyday Remembering

认知老化和日常记忆

• 批准号: 6401105
• 负责人: KATHLEEN C INSEL
• 金额: $ 7.23万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-15 至 2002-10-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6401105
• 关键词: aging; behavior prediction; behavioral /social science research tag; chemotherapy; clinical research; cognition; cognition disorders; cues; diagnosis design /evaluation; disease /disorder proneness /risk; functional ability; human old age (65+); human subject; mental disorder diagnosis; neuropsychological tests; nursing diagnosis; psychometrics; reinforcer; self care; short term memory; sign /symptom; therapy compliance

The purpose of this investigation is to describe the influence of cognitive ability, specifically executive function, on medication adherence among older adults (70 years and older) who are community dwelling, but often too frail or lacking in resources, to travel to a university setting to participate in a research project. Therefore, this investigation targets the less mobile members of the older community by using home visits thereby making it possible for individuals who are not as high functioning to participate. This investigation also examines the loading of two easy to administer cognitive tests that have been reported to reflect executive function and examines if these tests load on the same factor as the established neuropsychological tests for executive function. It is further hypothesized that symptoms will influence medication adherence and interact with performance on the cognitive battery to predict medication adherence. Medication adherence is an important selfcare activity impacting on health and well being, yet adherence may be particularly problematic for older adults who have been shown elsewhere to experience cognitive decline associated with normal aging.

本调查的目的是描述认知能力（特别是执行功能）对居住在社区但往往因身体虚弱或缺乏资源而无法前往大学就读的老年人（70 岁及以上）的药物依从性的影响参加一个研究项目。因此，本次调查以老年社区中流动性较差的成员为对象，通过家访的方式，使功能不那么高的个体也能参与其中。这项调查还检查了两种易于管理的认知测试的负载，据报道这些测试可以反映执行功能，并检查这些测试的负载是否与已建立的执行功能神经心理学测试相同。进一步假设症状将影响药物依从性并与认知电池的表现相互作用以预测药物依从性。药物依从性是影响健康和福祉的重要自我保健活动，但对于老年人来说，药物依从性可能尤其成问题，因为其他研究表明，他们会经历与正常衰老相关的认知能力下降。

项目成果

Executive function, working memory, and medication adherence among older adults.

老年人的执行功能、工作记忆和药物依从性。

• 发表时间: 2006-03
• 作者: Insel, Kathleen;Morrow, Daniel;Brewer, Barbara;Figueredo, Aurelio
• 通讯作者: Figueredo, Aurelio

The negative association of independent personality and medication adherence.

独立人格与药物依从性的负相关。

• 发表时间: 2006-06
• 影响因子: 2.8
• 作者: Insel, Kathleen C;Reminger, Sheryl L;Hsiao, Chao
• 通讯作者: Hsiao, Chao

Individualizing memory strategies to improve medication adherence.

个性化记忆策略以提高药物依从性。

• 发表时间: 2005-11
• 作者: Insel, Kathleen Collins;Cole, Lois
• 通讯作者: Cole, Lois