GRC on Second Messengers & Protein Phosphorylation

GRC 关于第二信使

• 批准号: 6672958
• 负责人: Kendall J Blumer
• 金额: $ 0.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-06-01 至 2006-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6672958
• 关键词: biological signal transduction; cardiovascular disorder; cardiovascular system; cell biology; cell differentiation; cell growth regulation; meeting /conference /symposium; neoplasm /cancer; phosphorylation; second messengers; travel

DESCRIPTION (provided by applicant): We are requesting partial support for operation of the Gordon Research Conference (GRC) on Second Messengers and Protein Phosphorylation, which has been held annually since the early 70's. Over the years this GRC has been the venue where research leading to several Nobel Prizes was first presented. The meeting is held annually at Kimball Union Academy in Meriden, New Hampshire, which provides a familiar and handicapped-accessible venue to promote open interaction among participants. The 2003 iteration of this GRC will begin on Sunday night June 8 and conclude on Thursday evening June 12. The conference focuses on signal transduction mechanisms that regulate cell growth, differentiation, survival and metabolism. A full understanding of these signaling mechanisms is scientifically and clinically important because their failure plays a direct role in contemporary health problems that affect millions of people worldwide, such as diabetes, obesity, aging, cancer, cardiovascular disease, neurodegeneration, and developmental disorders. The speakers are encouraged to integrate biochemical, structural, cell biological and genomic approaches that provide a comprehensive understanding of the molecular aspects of signaling mechanisms as they relate to disease. The plenary speaker has been selected to set the stage for the conference and to challenge the participants to think about signal transduction from novel perspectives. The conference will consist of 8 sessions, each with a discussion leader and four speakers, selected from investigators who have made important recent contributions. At least 20% of the speakers are women or members of minority groups. Speakers in each session will develop the structure and function of important paradigms in signal transduction and relate these systems to disease mechanisms and potential treatment strategies. The co-chairs will select 135 participants from applicants, including representatives from industry and academia, senior scientists, postdoctoral fellows and graduate students. A special effort will be made to recruit minority participants by a direct mailing program. Participants will be encouraged to present posters on new and interesting results each afternoon. Importantly, the conference provides a forum for young investigators to see the connection between fundamental scientific inquiry and the application of scientific methods to the design of efficacious interventions for human disease. To emphasize this goal, four poster presentations that complement the themes of the meeting will be selected for brief oral presentation during the main sessions.

描述（由申请人提供）：我们请求对第二信使和蛋白质磷酸化戈登研究会议 (GRC) 的运作提供部分支持，该会议自 70 年代初以来每年举行一次。 多年来，该 GRC 一直是多项诺贝尔奖研究成果首次发表的场所。 该会议每年在新罕布什尔州梅里登的金博尔联盟学院举行，该学院提供了一个熟悉且适合残疾人使用的场所，以促进参与者之间的开放互动。 GRC 的 2003 年迭代将于 6 月 8 日星期日晚上开始，并于 6 月 12 日星期四晚上结束。这次会议的重点是调节细胞生长、分化、生存和新陈代谢的信号转导机制。 充分了解这些信号机制在科学和临床上都很重要，因为它们的失败在影响全世界数百万人的当代健康问题中发挥着直接作用，例如糖尿病、肥胖、衰老、癌症、心血管疾病、神经退行性疾病和发育障碍。 鼓励演讲者整合生化、结构、细胞生物学和基因组方法，以全面了解与疾病相关的信号机制的分子方面。 全体会议发言人的选择是为了为会议奠定基础，并挑战参与者从新颖的角度思考信号转导。 会议将由 8 场会议组成，每场会议有一名讨论主持人和四名发言人，发言人均选自最近做出重要贡献的研究人员。 至少 20% 的演讲者是女性或少数群体成员。 每场会议的演讲者将发展信号转导中重要范例的结构和功能，并将这些系统与疾病机制和潜在的治疗策略联系起来。 联合主席将从申请者中选出135名参会人员，包括来自工业界和学术界的代表、资深科学家、博士后和研究生。 将特别努力通过直邮计划招募少数族裔参与者。 我们将鼓励参与者每天下午展示有关新的、有趣的结果的海报。 重要的是，这次会议为年轻研究人员提供了一个论坛，让他们了解基础科学探究与科学方法在设计人类疾病有效干预措施中的应用之间的联系。 为了强调这一目标，将选择四张与会议主题相辅相成的海报展示，在主要会议期间进行简短的口头展示。