Mechanisms of Membrane Transport Gordon Conference 2003

膜传输机制戈登会议 2003

• 批准号: 6677730
• 负责人: BLISS FORBUSH
• 金额: $ 1.76万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-06-15 至 2004-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6677730
• 关键词: biological transport; meeting /conference /symposium; membrane proteins; travel

DESCRIPTION (provided by applicant): Funds are requested to help support a Gordon Research Conference, Mechanisms of Membrane Transport, to be held from June 15-20 in 2003 at Holderness School, Plymouth, New Hampshire. This meeting continues a very successful series, held every two years, on topical subjects of high interest to the membrane transport field. This year we will highlight the tremendous advances in understanding that have been enabled by the recent availability of high-resolution structures of membrane channels and transporters. These developments are of great biological significance, and as outlined herein, are both timely and medically relevant. The subjects are important to a wide range of clinical disciplines, and have particular applicability to kidney and gastrointestinal function and neuronal excitability. The meeting will also incorporate advances in the physical basis for membrane protein structure, molecular dynamics modeling of solute movements through channels, and single-molecule approaches to elucidation of mechanism. They will naturally bring together scientists from a wide range of disciplines and promote fruitful interactions that otherwise would probably never occur. Relevant disciplines include biochemistry, biophysics, physiology, cell biology, molecular biology, genetics, pharmacology, and internal medicine. The program is organized to focus on selected transporter families for which crystal structures are available or will soon become available. The meeting includes 31 regular talks and 2 special talks, organized in 9 sessions. The speakers will plan their talks for a very mixed audience, and the attendance of students, fellows, and clinicians will be encouraged. The poster sessions will be strongly promoted, and further emphasized by the selection of four 'short selected talks'. Young investigators will be especially encouraged to attend, present their work, and participate in discussions.

描述（由申请人提供）： 要求资金帮助支持戈登研究会议，即膜运输机制，将于2003年6月15日至20日在新罕布什尔州普利茅斯的霍尔德尼斯学校举行。这次会议持续了一个非常成功的系列，每两年举行一次膜运输领域感兴趣的主题。今年，我们将强调膜通道和转运蛋白的高分辨率结构的近期可用性所带来的巨大理解进步。这些发展具有很大的生物学意义，如本文所述，既及时又具有医学上的相关性。这些受试者对广泛的临床学科很重要，并且对肾脏和胃肠道功能以及神经元兴奋性具有特殊的适用性。这次会议还将在物理基础上进行膜蛋白结构的进步，通过通道的溶质运动的分子动力学建模以及阐明机制的单分子方法。他们自然会将来自广泛学科的科学家汇集在一起​​，并促进卓有成效的互动，否则这些互动可能永远不会发生。相关学科包括生物化学，生物物理学，生理学，细胞生物学，分子生物学，遗传学，药理学和内科医学。该计划的组织为重点是精选的运输蛋白家族，为晶体结构可用或很快就可以使用。会议包括31次常规会谈和2次在9次会议上组织的特别演讲。演讲者将为非常混杂的听众计划演讲，并鼓励学生，研究员和临床医生的出席。海报会议将得到强有力的促进，并通过选择四个“简短的演讲”进一步强调。特别鼓励年轻的调查人员参加，介绍他们的工作并参加讨论。