HIV Prevention Among Adolescent Women

青春期妇女的艾滋病毒预防

• 批准号: 6696059
• 负责人: Jennifer Di Noia
• 金额: $ 49.01万
• 依托单位: INTERSYSTEMS, INC.
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-20 至 2005-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6696059
• 关键词: AIDS education /prevention; African American; DVD /CD ROM; HIV infections; Hispanic Americans; adolescence (12-20); behavioral /social science research tag; caucasian American; clinical research; clinical trial phase III; computer program /software; computer system design /evaluation; disease /disorder proneness /risk; female; health behavior; human subject; psychometrics; racial /ethnic difference

DESCRIPTION (provided by applicant): This Phase II SBIR will develop and test a theory-based, culturally relevant, and age-appropriate intervention for HIV risk reduction among ethnic-racially diverse early adolescent females aged 11 through 14 years. Drawing from the theoretical and empirical literature and Phase I process and outcome data, Phase II will draft prevention content. Following review by a panel of community-based professionals and sample of 48 ethnic-racially diverse girls, the intervention will be revised and programmed for CD-ROM delivery. The efficacy of the CD-ROM-mediated intervention will be examined in a group-randomized trial. Girls will be recruited through youth services agencies in greater New York City. Following random assignment of sites to experimental and control study arms, 980 girls will complete pretest outcome measurement batteries. Experimental arm youths will interact with the software in six weekly on-site sessions. Youths in both study arms will complete posttest and six-month follow-up batteries. Outcome analyses will determine the efficacy of the computer-mediated intervention, relative to no intervention, in reducing girls' HIV risk behaviors and variables hypothesized to influence these behaviors. Should the CD-ROM intervention prove effective, it will be disseminated through direct marketing efforts and through licensing agreements with distributors of youth-oriented health promotion and disease prevention programs.

描述（由申请人提供）：此II阶段SBIR将开发和测试一种基于理论的，具有文化相关性和适合年龄的干预措施，以降低11至14岁年龄的青少年早期的青少年早期女性中的艾滋病毒风险。第二阶段将从理论和经验文献以及第一阶段的过程和结果数据中汲取灵感。在由社区专业人士组成的小组审查和48个种族多元化女孩的样本之后，将对干预措施进行修订和编程以进行CD-ROM交付。 CD-ROM介导的干预措施的功效将在组随机试验中检查。女孩将通过大纽约市的青年服务机构招募。在将站点随机分配到实验和对照研究臂之后，980名女孩将完成预测试结果测量电池。实验性的ARM青年将在每周六次的现场会话中与该软件进行互动。两个学习武器的年轻人将完成后测和六个月的后续电池。结果分析将确定计算机介导的干预措施相对于没有干预的疗效，以减少女孩的艾滋病毒风险行为和被认为影响这些行为的变量。如果CD-ROM干预证明有效，则将通过直接营销工作以及与面向青年健康促进和疾病预防计划的分销商的许可协议来传播。