DUAL METHODS OF PROTECTION FROM PREGNANCIES AND STDS/HIV

预防怀孕和性病/艾滋病毒的双重方法

• 批准号: 6539474
• 负责人: CAROL F ROYE
• 金额: $ 32.66万
• 依托单位: HUNTER COLLEGE
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-07-01 至 2004-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6539474
• 关键词: African American; African Caribbean; Chlamydiaceae; Hispanic Americans; adolescence (12-20); behavioral /social science research tag; clinical research; condoms; counseling; disease /disorder prevention /control; female; female antifertility drug; human immunodeficiency virus; human subject; human therapy evaluation; outcomes research; questionnaires; racial /ethnic difference; safe sex /sex abstinence; sex behavior; sex education; sexually transmitted diseases; urinalysis; videotape /videodisc; women's health

DESCRIPTION (adapted from the applicant's abstract): Effective use of contraception to prevent STIs/HIV and pregnancy requires that a young woman who uses a hormonal method of contraception has a male partner(s) who uses condoms consistently, regardless of the nature of the relationship between the two young people, e.g. long-term or casual. The target population of the proposed project is inner-city minority adolescent women who use hormonal contraceptives. The proposed project builds on the results of the applicant's preliminary studies of contraceptive use with male and female inner-city teens and on programs reported in the literature which have been successful at increasing condom use by subjects at risk for sexually acquired HIV and other STIs. The programs that will be replicated in this study are the brief counseling arm of Project RESPECT and the video-based patient education intervention implemented and evaluated by the Educational Development Center (EDC). The video to be used in the proposed study will be tailor-made and will reflect the needs of the target population, as determined by selected theories and the findings of prior qualitative and quantitative studies with members of this population. Subjects will be randomized into one of the four treatment conditions: Arm 1- brief patient counseling and video-education; arm 2- brief education counseling only, arm 3-video education only, arm 4- usual care. The research question to be answered is. What is the enhanced efficacy of the combination of a brief patient counseling intervention (an adaptation of Arm 2 of Project RESPECT) and video-based patient education? The main outcome variable is self-reported condom use. Other outcome measures include incidence of other risk behaviors including number of occasional partners and number of new partners during the follow up interval. Incidence of Chlamydia (the most prevalent STI in the target population) during the follow-up period will be tracked using the ligase chain reaction (LCR) assay to detect C. trachmatis. The project will be implemented in Planned Parenthood clinics in New York City Young women will be recruited on-site. Those who consent will be given a pre-test questionnaire addressing their sexual behaviors. They will also be given a urine Chlamydia test. They will then be randomized into one of the 4 research arms, and will participate in the intervention at that visit. Three months after participation the young women will be given a post-test questionnaire to access for behavior change and a second Chlamydia test will be analyzed.

描述（改编自申请人的摘要）：有效利用 为预防性传播感染/艾滋病毒和怀孕而采取的避孕措施要求年轻女性 使用激素避孕方法 有一位使用避孕套的男性伴侣 始终如一，无论两者之间关系的性质如何 年轻人，例如长期或临时。拟议的目标人群 该项目针对使用激素的内城少数族裔青少年女性 避孕药具。拟议的项目建立在申请人的研究成果的基础上 内城区男性和女性青少年避孕药具使用情况的初步研究 以及文献中报道的已成功实施的计划 增加有性传播艾滋病毒和其他感染风险的受试者使用安全套的情况 性传播感染。本研究中将复制的程序是简短的 RESPECT 项目的咨询部门和基于视频的患者教育 由教育发展中心实施和评估的干预措施 （EDC）。拟议研究中使用的视频将是量身定制的，并将 反映由所选理论确定的目标人群的需求 以及之前与成员进行的定性和定量研究的结果 这个人口。受试者将被随机分配到四种治疗方法中的一种 条件：第 1 组 - 简短的患者咨询和视频教育；臂 2- 简短 仅教育咨询，arm 3 - 仅视频教育，arm 4 - 常规护理。这 要回答的研究问题是。增强功效是什么 结合简短的患者咨询干预（第 2 组的改编） RESPECT 项目）和基于视频的患者教育？主要成果 变量是自我报告的安全套使用情况。其他结果指标包括发生率 其他风险行为，包括偶尔性伴侣的数量和 后续期间的新合作伙伴。衣原体的发病率（最 目标人群中流行的性传播感染）在随访期间将 使用连接酶链式反应 (LCR) 检测来检测沙眼衣原体。 该项目将在纽约市的计划生育诊所实施 年轻女性将在现场招募。同意者将获得 针对他们的性行为的预测试问卷。他们也将是 进行尿液衣原体检测。然后他们将被随机分配到 4 组之一 研究部门，并将参加这次访问的干预。三 参与几个月后，年轻女性将接受一次后测 将进行调查问卷以获取行为改变和第二次衣原体测试 分析了。