CORE--VIROLOGY/BSL3 TISSUE CULTURE

核心--病毒学/BSL3 组织培养

• 批准号: 6646602
• 负责人: Andrew H Kaplan
• 金额: $ 12.95万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-07-01 至 2003-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6646602
• 关键词: AIDS; biohazard control; biomedical facility; human immunodeficiency virus; immune system; immunopathology; molecular biology; pathologic process; tissue /cell culture

The UCLA CFAR Virology Core Laboratory has provided HIV-related tissue culture and molecular biology support for UCLA researchers since 1991. The Core has served as a resource for studies of HIV pathogenesis and the associated immune dysfunction. Specifically, the Core acts as a focal point for development and application of novel technologies in HIV molecular virologic assessment and as a bridge between basic and clinical studies conducted at UCLA. The Core also provides training to new investigators in HIV biosafety procedures. The overall purpose of the Core is to provide state of the art techniques of molecular virologic assessment as well as traditional cell culture methods to UCLA researchers. By making the assays and facilities of the Virology Core Facility available to all investigators at UCLA who are studying any aspect of HIV infection, we have successfully fostered interactions between scientists in several departments at the UCLA School of Medicine as well as the Schools of Public Health and Dentistry. Specifically, we will: 1. Maintain storage facilities and serum repositories for UCLA investigators. 2. Provide a biosafety level 3 facility for UCLA investigators. 3. Provide training in the procedures required for biosafety level facilities for UCLA investigators. 4. Introduce novel assays for use by UCLA investigators. 5. Promote the use of our assays and facilities by clinical, basic, public health and behavioral investigators.

UCLA CFAR病毒学核心实验室提供了与HIV相关的组织 自1991年以来，对UCLA研究人员的培养和分子生物学支持。 核心已成为研究HIV发病机理和 相关的免疫功能障碍。具体而言，核心充当焦点 新技术在HIV中的开发和应用点 分子病毒学评估，作为基本和临床之间的桥梁 在UCLA进行的研究。核心还为新的培训提供了培训 HIV生物安全程序的研究人员。核心的总体目的 是提供分子病毒学技术的最先进技术 评估以及对UCLA的传统细胞培养方法 研究人员。通过制作病毒学核心的测定和设施 UCLA的所有研究人员都可以使用任何研究 艾滋病毒感染的方面，我们成功培养了互动 加州大学洛杉矶分校医学院的多个部门的科学家之间 以及公共卫生和牙科学校。具体来说，我们 将要： 1。维护UCLA的存储设施和血清存储库 调查人员。 2。为UCLA调查人员提供生物安全3级设施。 3.提供生物安全水平所需程序的培训 UCLA调查人员的设施。 4。介绍加州大学洛杉矶分校调查人员使用的新颖测定法。 5。通过临床，基本，公众促进我们的测定和设施的使用 健康和行为研究人员。