Using novel phenomics technology for environmental sensitivity prediction in marine invertebrates

利用新型表型组学技术预测海洋无脊椎动物的环境敏感性

• 批准号: 2274014
• 金额: --
• 依托单位: Plymouth University
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2019
• 资助国家: 英国
• 起止时间: 2019 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2274014
• 关键词: Using; novel; phenomics; technology; environmental

This PhD will apply a new, cutting-edge technology, EmbryoPhenomics, to develop novel tools for predicting environmental sensitivity in marine invertebrates. The accurate prediction of how organisms will respond to global change represents a significant scientific challenge but is essential for developing policy decisions and mitigation strategies. Phenomics is a new, technology-enabled approach that uses the high-throughput acquisition of high-dimensional data of the observable phenotype (i.e. morphology, physiology and behaviour) to measure biological responses more robustly and provide a more holistic understanding of the mechanisms underpinning sensitivity. EmbryoPhenomics uses bio-imaging and advanced image analysis to measure the sensitivity of early developmental stages in aquatic species with different life history strategies and will be used to produce novel, sub-lethal phenomic end points that can be used as predictive tools.

该博士将采用一种新的尖端技术，即胚胎素学，以开发用于预测海洋无脊椎动物环境敏感性的新颖工具。对生物如何应对全球变化的准确预测是一项重大的科学挑战，但对于制定政策决策和缓解策略至关重要。现象学是一种新的，具有技术的方法，它使用可观察表型的高维数据（即形态学，生理学和行为）的高维数据的高通量获取，以更加稳健地衡量生物学反应，并提供对支撑敏感性机制的更全面的理解。胚胎素学使用生物成像和高级图像分析来衡量具有不同生活史策略的水生物种早期发育阶段的敏感性，并将用于生成可用作预测工具的新型，杀致命的现象终点。