Core--Animal facility

核心--动物设施

• 批准号: 6659261
• 负责人: VINCENT M MONNIER
• 金额: $ 9.46万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-01 至 2003-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6659261
• 关键词: animal colony; biomedical facility; diabetes mellitus; disease /disorder model; laboratory mouse; laboratory rat

Summary ANIMAL CORE The objective of the Animal Core is to provide investigators of the Program Project with scientific and technical support for the design and execution of their studies. The specific aims of this core are: 1. To induce diabetes in animals and maintain the animals in a healthy state (routinely monitored for compliance with standards of health appropriate for diabetic animals) and in carefully controlled levels of glycemic control, 2. To coordinate the acquisition and distribution of tissues and body fluids from experimental animals among Program Project investigators, 3. To provide assistance with scientific and execution of protocols involving special diet and pharmacological treatments in animals, and 4. To provide training for new investigators of the Program Project in the use of animal models of diabetes and its complications. Service to the Investigators of the Program Project will be provided by a team consisting of the director of our unit for animal studies (V. Monnier, MD, T. Kern, PhD), and a 60% FTE Research Assistant who will assume the day-to-day operation of the facility in collaboration with the staff of the Animal Resources Center at CWRU).

摘要 动物核心 动物核心的目标是为该计划项目的研究人员提供设计和执行研究的科学和技术支持。该核心的具体目标是： 1. 诱发动物糖尿病并维持动物健康状态（定期监测是否符合适合糖尿病动物的健康标准）和仔细控制血糖控制水平， 2. 协调项目研究人员获取和分配实验动物的组织和体液， 3. 为涉及动物特殊饮食和药物治疗的方案的科学和执行提供帮助，以及 4. 为项目项目的新研究人员提供培训在动物模型的使用上糖尿病及其并发症。为该计划项目的研究人员提供的服务将由我们动物研究部门的主任（医学博士 V. Monnier、博士 T. Kern）和一名 60% FTE 研究助理组成的团队提供，该助理将承担当天的工作-与 CWRU 动物资源中心的工作人员合作进行设施的日常运营）。