Materials Properties

材料特性

• 批准号: 6443104
• 负责人: DANIEL P NICOLELLA
• 金额: $ 15.28万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-06-01 至 2007-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6443104
• 关键词: biomaterial evaluation; biomaterials; biomechanics; composite resins; dental bonding material; dental stress analysis

DESCRIPTION (provided by applicant): The objective of this project is to aid in the development of successful dental restorative materials by evaluating a number of material properties and characteristics of newly developed composite resin. The general hypothesis is that low shrinkage nanofiller and conventional filler composites will have a balance of mechanical and physical properties superior to a clinically successful, commercially available reference composite. As such, similar properties of a conventional unfilled model system (Bis-GMA based), a conventional filled model system (glass or silica filler in a bis-GMA based resin), and a commercially available reference composite will also be determined. To test the general hypothesis, three specific aims are proposed. The transverse strength, fracture toughness, shrinkage and morphological characteristics of the restorative composite resins will be measure in specific aim 1. Aim 2 will measure selected mechanical (compressive strength, elastic modulus, surface roughness and wear resistance) and physical properties (depth of cure, water sorption, coefficient of thermal expansion, rheology, radiopacity, and color stability) of restorative composite resins to identify favorable resin composite formulations. The shear bond strength of the restorative composite resin, in the presence and absence of OP-1 tertiary dentin-stimulating treatment, using a commercially available dentin bonding agent will be measured in Aim 3. In aim 3, Scotchbond Multipurpose will be used as the dentin bonding agent used. It is known that a series of materials tests for prototype resin composites will play a significant role in guiding the evolution, refinement and eventual scale up of the materials used to develop a novel restorative system. Thus, the outcome of these comprehensive tests will allow newly developed resin composites to be compared to a clinically successful restorative material. It is also through these comprehensive tests that the ultimate formulation for model resin composites will be selected for eventual evaluation in the oral environment.

描述（由申请人提供）：该项目的目的是协助 通过评估成功的牙科修复材料的开发 新开发的复合材料的材料特性和特征的数量 树脂。一般的假设是低收缩纳米填料和常规的假设 填充复合材料将具有机械和物理特性的平衡 优于临床成功的市售参考 合成的。因此，常规未填充模型系统的类似属性 （基于BIS-GMA），一种常规填充的模型系统（玻璃或二氧化硅填充物 基于BIS-GMA的树脂）和商业可用的参考复合材料将 也可以确定。为了检验一般假设，三个具体目标是 建议的。横向强度，断裂韧性，收缩和 恢复性复合树脂的形态特征将是 在特定目标1中的测量。AIM2将测量选定的机械（压缩 强度，弹性模量，表面粗糙度和耐磨性）和物理 特性（治愈深度，水吸附，热膨胀系数， 修复性复合树脂的流变学，放射性和颜色稳定性） 确定有利的树脂复合制剂。剪切键强度 在存在和不存在OP-1三级的情况下，恢复性复合树脂 使用市售的牙本质粘结，牙本质刺激治疗 代理将在AIM 3中测量。在AIM 3中，将使用Scotchbond多用途 如使用牙本质键合剂。众所周知，一系列材料测试 对于原型树脂复合材料，将在指导指导方面发挥重要作用 进化，改进和最终规模，用于开发用于开发的材料 新颖的恢复系统。因此，这些全面测试的结果将 将新开发的树脂复合材料与临床上进行比较 成功的修复材料。这也是通过这些全面测试 将选择模型树脂复合材料的最终配方 最终在口腔环境中进行评估。