UCI Multidisciplinary Exercise Sciences Training Program

UCI 多学科运动科学培训计划

• 批准号: 6593230
• 负责人: Kenneth M. Baldwin
• 金额: $ 11.67万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-05-01 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6593230
• 关键词: UCI; Multidisciplinary; Exercise; Sciences; Training

DESCRIPTION (provided by applicant): There continues to be growing recognition that exercise and inactivity play important roles in many disease processes. The goal of this training grant proposal is to establish a strong and rich research training environment for M.D.s and Ph.D.s interested in exercise science. The underlying programmatic theme of the training program is "integrative/translational" science. The program consists of three core groups: the Molecular Physiology, Core Group, the Svstems Physiology Core Group, and the Clinical Applications Core Group. The emphasis of these cores is in skeletal muscle, cardiovascular and respiratory physiology, neurobiology of activity, rehabilitation, and metabolism given that these areas of research represent the focus of the Program Faculty, and represent areas of extensive on-going interactions. An integrated/translational approach is especially important in exercise science because of the profound role that physical activity is now known to play in human health. Postdoctoral fellows will interact with the faculty and other trainees through a formal didactic program, seminars, journal clubs, and research-in-progress discussions. At the beginning of the program each fellow will work with the Executive Committee to select a primary and secondary research emphasis designed to reflect an appropriate diversity of topics in exercise science. These emphases will be selected from the basic science cores. Trainees will become familiar with animal and cell model systems and state-of-the-art approaches to human performance testing, thereby facilitating the translation from these systems to human research and, ultimately to clinical applications. For this latter objective, the Human Performance Laboratory at the U.C. Irvine GCRC will play an important role as it is funded specifically to support translational research in an environment that optimizes the safety and quality of human investigation. Additionally, we have developed an innovative Clinical Applications Core that will significantly enhance the translational theme of this training grant. This proposed training program is designed to introduce postdoctoral trainees to new disciplines as they continue to hone skills and approaches mastered in the predoctoral years. For postdoctoral M.D.s, the program will attract individuals seriously interested in becoming independent investigators. Exercise physiology is not a separate ACGME-recognized specialty or subspecialty; consequently, M.D.s pursuing postdoctoral training in this program must be committed to academic careers. For Ph.D.s, the program will be best suited for basic scientists who see their academic careers involving clinical interaction either through direct human research or as members of faculties of medical schools where translational research activity is likely to be encouraged.

描述（由申请人提供）： 人们越来越认识到运动和不活动在许多疾病过程中发挥着重要作用。该培训资助提案的目标是为对运动科学感兴趣的医学博士和博士建立一个强大而丰富的研究培训环境。培训计划的基本主题是“综合/转化”科学。该计划由三个核心组组成：分子生理学核心组、系统生理学核心组和临床应用核心组。这些核心的重点是骨骼肌、心血管和呼吸生理学、活动神经生物学、康复和新陈代谢，因为这些研究领域代表了项目学院的重点，并代表了广泛持续互动的领域。综合/转化方法在运动科学中尤其重要，因为现在已知体育活动在人类健康中发挥着深远的作用。博士后研究员将通过正式的教学计划、研讨会、期刊俱乐部和正在进行的研究讨论与教师和其他学员互动。在项目开始时，每位研究员将与执行委员会合作，选择主要和次要的研究重点，旨在反映运动科学主题的适当多样性。这些重点将从基础科学核心中选择。学员将熟悉动物和细胞模型系统以及最先进的人体性能测试方法，从而促进从这些系统到人类研究的转化，并最终转化为临床应用。为了实现后一个目标，加州大学人类表现实验室尔湾 GCRC 将发挥重要作用，因为它专门资助支持在优化人类研究的安全性和质量的环境中进行转化研究。 此外，我们还开发了一个创新的临床应用核心，它将显着增强本次培训资助的转化主题。这项拟议的培训计划旨在向博士后学员介绍新学科，让他们继续磨练博士前时期掌握的技能和方法。对于博士后医学博士来说，该计划将吸引对成为独立研究人员非常感兴趣的个人。运动生理学不是一个单独的 ACGME 认可的专业或亚专业；因此，在该项目中接受博士后培训的医学博士必须致力于学术事业。对于博士生来说，该项目最适合基础科学家，他们认为自己的学术生涯涉及通过直接人类研究进行临床互动，或者作为可能鼓励转化研究活动的医学院教员。