PILOT PROJECTS

试点项目

• 批准号: 6563167
• 负责人: DAVID W CRABB
• 金额: $ 13.07万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-12-01 至 2002-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6563167
• 关键词: X ray crystallography; alcohol dehydrogenase; alcoholic beverage consumption; alcoholic liver cirrhosis; alcoholism /alcohol abuse; aldehyde dehydrogenases; behavioral /social science research tag; behavioral genetics; biomarker; brain circulation; enzyme activity; fetal alcohol syndrome; genetic models; genetic strain; genetic susceptibility; genetically modified animals; genotype; hydrolase; laboratory mouse; laboratory rat; neurogenetics; phospholipase D; preference; serotonin receptor; statistics /biometry; ultrasound blood flow measurement

The Pilot Project Component will continue into years 11-15 of the Indiana Alcohol Research Center. This Component is a mechanism for funding promising, innovative research, for attracting new investigators to alcohol research, for developing methodologies that may be of use to other investigators in the Center, and exploring areas of long-range relevance to the overall Center aims. This Component has had a major influence on the growth of alcohol research on this campus over the past 10 years. We believe that there has been a remarkable rate of success in obtaining independent funding subsequent to the receipt of pilot funding, for either new investigators or more senior ones who have entered new areas of research. Hence we propose to continue this component at the same level of activity as now exists. Two new pilots will be initiated in year 10 of the current funding period, and will continue into year 11. Thereafter, two new projects will be initiated in years 11 and 12, so that a total of four pilots are active each year. Additional pilots were received in excess of our ability to fund them, and these investigators, as well as other new investigators, are expected to submit applications for funding in years 13-15. The Pilot Project component is overseen by David Crabb with input from T. -K. Li and Richard Rose and the External Advisory Committee. Current and future pilots are chosen after posting notices of availability of funding and submission of a written application. Preference will continue to be given to new investigators first, established investigators new to alcohol research second, and lastly to established investigators in alcohol research. Progress is monitored by written yearly reports and presentation of results at the annual meeting or retreat.

试点项目组件将持续到11 - 15年 印第安纳州酒精研究中心。 该组件是一种机制 资金有希望的创新研究，以吸引新的调查员 进行酒精研究，用于开发可能使用的方法 中心的其他调查人员，探索远程的领域 与整个中心的目的有关。 该组件有一个专业 过去对该校园的酒精研究的影响 10年。 我们认为，在 在收到试点资金后获得独立资金， 对于新的调查人员或已进入新的调查员 研究领域。 因此，我们建议在 与现在相同的活动水平。将在 当前资金期的第10年，将持续到第11年。 此后，将在11年和12年内启动两个新项目，以便 每年共有四名飞行员活跃。 其他飞行员是 收到了我们资助他们的能力，这些调查员， 以及其他新调查人员，应提交申请 13 - 15年的资金。 试点项目组件由David Crabb负责 来自T. -K。李和理查德·罗斯和外部咨询委员会。 发布可用性通知后，选择了当前和未来的飞行员 资金和提交书面申请。 偏好会 首先，继续向新的调查人员交给新的调查员 酒精研究的新手第二，最后是 酒精研究。 进度由书面年度报告监控，并且 在年度会议或务虚会上表现结果。