TRAINING IN DEVELOPMENTAL BIOLOGY OF MEMBRANE TRANSPORT

膜运输发育生物学培训

• 批准号: 6636769
• 负责人: Lisa M. Satlin
• 金额: $ 22.58万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-08-07 至 2005-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6636769
• 关键词: TRAINING; DEVELOPMENTAL; BIOLOGY; MEMBRANE; TRANSPORT

DESCRIPTION (Adapted from applicant's description): The objective of this proposal is to train pediatric M.D. and M.D./Ph.D. physician-scientists for successful careers as independent investigators in the field of developmental physiology and cell biology, specifically as it relates to understanding the ontogeny and regulation of membrane transport. Three priorities for research training have been identified: 1) To identify and characterize transport proteins and their functional interactions as they relate to cell growth, differentiation and the maintenance of homeostasis; 2) To determine the developmental and genetic bases for inherited and acquired disorders of membrane transport; and 3) To develop new therapeutic strategies (e.g., gene therapy) for disorders of membrane transport. The inclusion of both clinical and basic science faculty preceptors with research interests and expertise in these related fields will provide a basic research training experience. All candidates for this training program will be expected to devote a minimum of three years to research training.

描述（改编自申请人的描述）：此目的 提议是培训儿科医学博士和医学博士/博士。医师科学家 作为发展领域的独立研究者取得了成功的职业生涯 生理学和细胞生物学，特别是与理解 个体发育和膜运输的调节。 研究的三个优先事项 培训已确定： 1) 识别和描述运输 蛋白质及其与细胞生长相关的功能相互作用， 分化和体内平衡的维持； 2）确定 遗传性和获得性疾病的发育和遗传基础 膜运输； 3) 开发新的治疗策略（例如基因治疗） 疗法）治疗膜运输障碍。 包括临床 以及具有研究兴趣和专业知识的基础科学教师导师 这些相关领域将提供基础研究培训经验。 全部 该培训计划的候选人将被期望投入至少 三年的研究培训。