Community Based Research of Autoimmune Disease and Asth*

基于社区的自身免疫性疾病和哮喘研究*

• 批准号: 6524822
• 负责人: John Edward Vena
• 金额: $ 32.22万
• 依托单位: STATE UNIVERSITY OF NEW YORK AT BUFFALO
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-30 至 2006-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6524822
• 关键词: asthma; autoimmune disorder; behavioral /social science research tag; clinical research; community; environmental contamination; environmental health; health care service planning; health science research analysis /evaluation; human subject; information dissemination; medically underserved population; social change; social cooperation; systemic lupus erythematosus; urban poverty area

DESCRIPTION (provided by applicant): The investigators propose that the Environment and Society Institute (ESI) and the Department of Social and Preventive Medicine of the University of Buffalo (UB) continue community participatory research projects currently underway in two targeted communities in Buffalo, New York. Their plan is to strengthen the infrastructural and organizational requirements for the operation of a community environmental health response team which will improve research quality and relevance and maintain the community outreach that will engender community participation at all levels of the research process, including dissemination of the findings. The community and scientist partners have developed and are implementing an outcome-based research agenda focusing on two targeted geographic areas: 1) a community on the east-side of Buffalo concerned with pollution from toxic waste sites and point sources of pollution and a cluster of autoimmune disease, and 2) the westside of Buffalo near a high-traffic corridor with elevated exposures to diesel exhaust and documented higher prevalence of asthma. The research teams in place consist of investigators and staff from the University at Buffalo and an active steering committee with working groups for each community-based study. Specific tasks outlined in the methodology are (1) further implementation of the research agenda, (2) development of communication and dissemination strategies, (3) evaluation of the participatory process, and (4) evaluation of the completion of the research objectives. These steering committees and workgroups provide a forum where science is integrated with decision-making processes. The research teams in place will serve as a scientific and educational resource for the community and will facilitate integration of activities related to health assessment, risk communication, and action. A partnership will be strengthened by the activities proposed herein between research scientists, primary care providers, and citizens, in two high-risk, underserved, poor, minority populations that appear to be adversely impacted by environmental insults. Over the five-year period in each of the study areas, research objectives will include further documentation of the prevalence of disease, validation of diagnosis and organization of exposure assessment protocols, design and implementation of analytic studies, establishment of surveillance systems, dissemination of findings and the development and implementation of interventions.

描述（由申请人提供）： 调查人员建议环境与社会研究所（ESI）和 布法罗大学的社会和预防医学系 （UB）继续目前正在进行的社区参与研究项目 纽约布法罗的两个有针对性的社区。 他们的计划是加强 运营的基础设施和组织要求 社区环境健康响应团队将改善研究 质量和相关性，并保持社区宣传 社区参与研究过程的各个级别，包括 分散发现。 社区和科学家合作伙伴有 开发并正在实施基于结果的研究议程 两个有针对性的地理区域：1）布法罗东侧的一个社区 与有毒废物站点的污染和污染源有关 和一群自身免疫性疾病，以及2）布法罗的西侧 高流量的走廊，柴油排气的暴露率高并记录下来 哮喘的较高患病率。 研究团队的到位包括 大学的调查人员和工作人员在布法罗和积极的转向 每个基于社区的研究的工作组委员会。 特定任务 方法论中概述的是（1）进一步实施研究 议程，（2）发展沟通和传播策略， （3）评估参与过程，（4）评估 完成研究目标的完成。 这些转向委员会和工作组提供了一个论坛，科学是 与决策过程集成。 到位的研究团队将 作为社区的科学和教育资源，将 有助于整合与健康评估，风险有关的活动 沟通和行动。 合作伙伴关系将由 研究科学家，初级保健之间提出的活动 提供者和公民，两个高风险，服务不足，贫困，少数人 似乎受到环境侮辱的不利影响的人群。 在每个研究领域的五年中，研究目标将 包括进一步的疾病患病率的记录，验证 诊断和组织暴露评估方案，设计和 分析研究的实施，监视系统的建立， 调查结果的传播以及发展和实施 干预措施。