MULTICHANNEL ARRAY TECHNIQUES: MULTICHANNEL RECORDING & ELECTRODES

多通道阵列技术：多通道记录

• 批准号: 6505241
• 负责人: DAVID JAMES ANDERSON
• 金额: $ 20.08万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-01 至 2002-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6505241
• 关键词: Mammalia; animal tissue; bioengineering /biomedical engineering; biomaterials; biomedical equipment development; biomedical resource; ear; medical rehabilitation related tag; nervous system; prosthesis; technology /technique

The placement of microprobes into deep brain structures such as hippocampus, Scarpa's ganglion, inferior colliculus, cochlear nucleus and deep cortical layers continues to be a growing area of interest for our external collaborators. Dr. Buzsaki's presentations at national meetings as well as his publications have stirred a great deal of interest from those recording in hippocampus. Challenges in using the probes for these preparations include holding the probe and maintaining a straight trajectory during insertion, accurate site placement in small regions well below the brain surface, and stabilization after insertion. We are working with the listed group of collaborative researchers to solve these problems. Probes with long shanks tend to bend during insertion. Several investigators are using cannular preparations to insert probes into deep structures. Others are exploring the coatings to enhance rigidity, or attachment of small, more rigid structures to the back of the substrate. New methods for insertion are also being evaluated for their ability to enhance the straightness of insertions. Custom probes have been designed by the above investigators and have been fabricated and provided by the Center mounted and bonded to desired connectors. The work done within this scientific sub-project benefits many investigators with new placement techniques, not only in deep brain structures but in other areas as well.

将微探针的放置在深脑结构中，例如 海马，Scarpa的神经节，下丘，耳蜗核 深层皮质层仍然是一个增长的感兴趣领域 对于我们的外部合作者。 Buzsaki博士在 全国会议以及他的出版物激起了伟大的激动人心 在海马录音的人中感兴趣的交易。 挑战 使用这些制剂的探针包括持有探针和 在插入，准确的位点保持直线轨迹 放置在大脑表面以下的小区域，并且 插入后稳定。 我们正在与上市组合作 协作研究人员解决这些问题。 与 插入过程中长柄倾向于弯曲。 几个调查人员是 利用罐头制剂将探针插入深层结构中。 其他人正在探索涂料以提高刚性或依恋 基板背面的小，更刚性的结构。 新的 还评估了插入方法的能力 增强插入的直率。 自定义探针已经 由上述调查人员设计，已制造，并且 由中心安装并粘合到所需的连接器。 这 在这项科学的子项目中完成的工作使许多人受益 具有新位置技术的调查员，不仅在深脑中 结构，但在其他领域也是如此。