Core--Histopathology

核心--组织病理学

• 批准号: 6443381
• 负责人: TRENTON R SCHOEB
• 金额: $ 13.16万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-01 至 2002-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6443381
• 关键词: biomedical facility; environmental toxicology; hazardous substances; histology

The histology core laboratory will be responsible for producing high- quality, uniformly sectioned and stained, histologic slides of animal tissues in support of projects 1,2, and 5. The core will utilize the physical facilities of the University of Florida ICBR Affiliate Research histology and Biomechanics Core Laboratory (RHBCL), which has all of the necessary equipment for routine histology for routine histology, including an automated tissue processor, paraffin embedding station, rotary and sliding microtomes, and a programmable slide stainer, cover slipper, microscope, and miscellaneous equipment. The core will provide an experienced, certified histotechnicians dedicated to support of this program project. Investigators of each component project will provide fixed, trimmed tissues, which the technician will embed, section, and stain as required. Special processing for immunohistochemistry and a variety of special stains will be available as needed. The histotechnician supported by this core will be supervised by Dr. Schoeb, who also is co- scientific advisor for soft tissues for the RHBCL. Dr. Schoeb also will provide interpretation of slides and consultation regarding technical aspects of histopathology for component projects, particularly projects 1 and 5, for which he is not specifically listed as co-investigator.

组织学核心实验室将负责生产高质量的，统一的分割和染色，动物组织的组织学滑梯，以支持项目1,2和5。电台，旋转和滑动微型分子，以及可编程的滑动污渍，盖拖鞋，显微镜和其他设备。核心将提供经验丰富的，认证的历史学家，致力于支持该计划项目。每个组件项目的研究人员将提供固定的修剪组织，技术人员将根据需要将其嵌入，部分和染色。可以根据需要进行免疫组织化学和各种特殊污渍的特殊加工。由该核心支持的组织技术学家将由Schoeb博士进行监督，Schoeb博士也是RHBCL软组织的合作顾问。 Schoeb博士还将提供有关组件项目组织病理学技术方面的幻灯片和咨询的解释，尤其是项目1和5，他并未被专门列为共同投资者。