PREDOCTORAL TRAINING PROGRAM IN MOLECULAR THERAPEUTICS

分子治疗学博士前培训计划

• 批准号: 6498529
• 负责人: PAUL N MACDONALD
• 金额: $ 13.96万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-07-01 至 2006-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6498529
• 关键词: PREDOCTORAL; TRAINING; PROGRAM; MOLECULAR; THERAPEUTICS

DESCRIPTION: (provided by applicant) This new application requests support for the Predoctoral Training Program in Molecular Therapeutics at Case Western Reserve University (CWRU). The application requests support for three predoctoral students in the first year of support with a total funding period of five years. The global objective of this training program is to provide predoctoral students with the necessary knowledge base and skills to begin independent investigative and teaching careers in the pharmacological sciences. The immediate goals of the program are to foster the training, evaluation and counseling of students throughout their training and in meeting their long-term career objectives, The program itself is composed of broad-based, didactic training in fundamental principles of modem pharmacology that is integrated into an interdisciplinary, multi-faceted research training experience. Both the didactic and research components emphasize molecular, cellular, biochemical, and genetic approaches to understand mechanisms of drug action and the use of therapeutic agents as important tools to probe physiological and pathophysiological processes. The didactic component consists of required core courses that emphasize fundamental principles in pharmacology as wen as advanced electives that build on core principles. Research projects center on three major focal areas, 1) receptors and signaling, 2) hormone responsive malignancies, and 3) pharmacogenomics. Continuing training is offered in a number of key areas including mentoring, verbal/written communication skills, and critical analysis of the scientific literature, using a variety of learning formats including journal clubs, seminars, evening colloquia, workshops, and retreats. This interdisciplinary training program consists of 33 faculty trainers from 11 different basic and clinical departments affiliated with the School of Medicine at CWRU. The trainers in this program are a highly interactive, collaborative group that have considerable experience in training at both the predoctoral and postdoctoral levels. They are leaders in their respective fields and have generated over $13 million dollars in national funding to support predoctoral research in this program. In summary, this program will provide predoctoral students with advanced training, education, and the technical experience that is necessary for these students to become the future leaders in education and research in the pharmacological sciences.

描述：（由申请人提供）此新申请要求支持Case Western Reserve University（CWRU）分子治疗前培训前培训计划的支持。该申请在支持的第一年中要求支持三名前学生的支持，总资助期为五年。该培训计划的全球目标是为前学生提供必要的知识库和技能，以开始在药理学科学的独立调查和教学职业。该计划的直接目标是在整个培训中培养学生对学生的培训，评估和咨询，并在实现其长期职业目标时，该计划本身由基于广泛的基础，教学培训组成，用于调制解调器药理学的基本原理，这些原理被整合到跨学科的多方，多方面的研究培训经验中。教学成分和研究组成部分都强调了分子，细胞，生化和遗传方法，以了解药物作用机制，以及使用治疗剂作为探测生理和病理生理过程的重要工具。教学成分由所需的核心课程组成，这些课程强调药理学中的基本原则是基于核心原则的高级选修课。研究项目集中在三个主要焦点区域：1）受体和信号传导，2）激素反应性恶性肿瘤和3）药物基因组学。在许多关键领域提供了持续的培训，包括指导，口头/书面沟通技巧以及对科学文献的批判性分析，并使用各种学习格式，包括期刊俱乐部，研讨会，晚间讲话，讲习班，讲习班和务虚会。该跨学科培训计划由来自CWRU医学院的11个不同基本和临床部门的33名教师培训师组成。该计划的培训师是一个高度互动的协作小组，在培训前和博士后水平都具有丰富的培训经验。他们是各自领域的领导者，并为支持该计划中的专业研究提供了超过1300万美元的全国资金。总而言之，该计划将为这些学生提供高级培训，教育以及这些学生成为药理学教育和研究领导者所必需的技术经验。