Postnatal Exposure to Oxytocin--Female Reproductive Behavior

产后接触催产素——女性生殖行为

• 批准号: 6583764
• 负责人: BRUCE S CUSHING
• 金额: $ 12.97万
• 依托单位: UNIV OF MARYLAND, COLLEGE PARK
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-03-01 至 2003-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6583764
• 关键词: behavioral /social science research tag; exploratory behavior; female; hormone regulation /control mechanism; laboratory rat; mature animal; newborn animals; ovariectomy; oxytocin; progesterone; reproductive development; sex behavior; social behavior; vole

The purpose of this project is the analysis of the effects of neonatal oxytocin (OT) manipulations on subsequent sexual and social behaviors in prairie voles. This project will focus on female socio-sexual behavior and an index of responsivity to estrogen in female rats and voles that have been exposed to neonatal OT manipulations. In addition, the effects of OT on these behaviors will be studied in adulthood as a function of neonatal manipulations of OT. Other behavioral endpoints included exploratory behavior will be used in conjunction with these studies.

该项目的目的是分析新生儿催产素（OT）操作对草原田鼠随后的性行为和社会行为的影响。该项目将重点关注暴露于新生儿 OT 操作的雌性大鼠和田鼠的雌性社会性行为和雌激素反应指数。此外，将在成年期研究 OT 对这些行为的影响，作为新生儿 OT 操作的函数。包括探索行为在内的其他行为终点将与这些研究结合使用。