Gordon Research Conference on Tetrapyrroles

戈登四吡咯研究会议

• 批准号: 6506009
• 负责人: GLORIA C. FERREIRA
• 金额: $ 1万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-06-01 至 2003-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6506009
• 关键词: meeting /conference /symposium; tetrapyrroles; travel

DESCRIPTION (provided by applicant): This application requests support for the 19th Gordon Research Conference on the Chemistry and Biology of Tetrapyrroles, to be held at Salve Regina University, Newport, RI, from July 14-19, 2002. This biennial interdisciplinary conference has stimulated collaborations between basic biologists, chemists and clinicians interested in Tetrapyrroles for more than three decades. In association with proteins, Tetrapyrroles serve diverse roles as biological redox catalysts, for harvesting of light energy, for oxygen activation/delivery and as signaling molecules. Free Tetrapyrroles are also essential nutrients (e.g., vitamin B12), serve as regulators of gene expression (e.g., hemes) and have been utilized as therapeutic agents (e.g., photodynamic cancer therapy, target delivery of radionuclides). Owing to their photodynamic activity, toxicity and lipophilicity, the accumulation of Tetrapyrroles (e.g., porphyrins, bilirubin) is associated with numerous pathologies of the skin, liver and brain. For these reasons, this conference represents an important venue for exchange between basic and applied researchers on Tetrapyrroles and for refinement of new tools and therapies which are under development by the biomedical industry. Funds requested in this application are targeted to support investigators who have not previously had the opportunity to attend this conference. A special effort has been placed in promoting participation of young investigators. One of two new sessions has been added to highlight recent developments and what the future promises in genomics, proteomics and protein technologies; the second new session will focus on the molecular regulatory mechanisms of erythropoiesis and apoptosis and their implications in relation to blood and liver disorders. There will be 22 invited speakers, a plenary lecturer and 8 discussion leaders, who have been selected for their scientific excellence, recent innovative work and breadth of the program. The remaining 100 conferees will be chosen to ensure a broad representation of women, ethnicity and young scientists from various disciplines in academia, medical research institutions and industry. Strengths of this ongoing Gordon conference are its disciplinary diversity, focus on new unpublished work, time for discussion, informal atmosphere, and ban on dissemination of conference proceeding.

说明（由申请人提供）：本申请请求支持将于 2002 年 7 月 14 日至 19 日在罗德岛州纽波特萨尔维里贾纳大学举行的第 19 届四吡咯化学和生物学戈登研究会议。该两年一度的跨学科会议三十多年来，促进了对四吡咯感兴趣的基础生物学家、化学家和临床医生之间的合作。与蛋白质结合，四吡咯发挥多种作用，例如生物氧化还原催化剂、光能收集、氧活化/输送以及信号分子。游离四吡咯也是必需营养素（例如维生素 B12），作为基因表达的调节剂（例如血红素），并已被用作治疗剂（例如光动力癌症治疗、放射性核素的靶向递送）。由于其光动力活性、毒性和亲脂性，四吡咯（例如卟啉、胆红素）的积累与皮肤、肝脏和大脑的多种病理有关。由于这些原因，本次会议成为四吡咯基础和应用研究人员之间交流以及完善生物医学行业正在开发的新工具和疗法的重要场所。本申请中请求的资金旨在支持以前没有机会参加本次会议的研究人员。我们特别努力促进年轻研究者的参与。增加了两个新会议之一，以强调基因组学、蛋白质组学和蛋白质技术的最新进展以及未来的前景；第二场新会议将重点关注红细胞生成和细胞凋亡的分子调节机制及其对血液和肝脏疾病的影响。将有 22 名受邀演讲者、一名全体讲师和 8 名讨论领袖，他们是因其卓越的科学成就、近期的创新工作和项目的广度而被选中的。剩下的 100 名参会者将被选出，以确保来自学术界、医学研究机构和工业界各个学科的女性、种族和年轻科学家的广泛代表性。正在进行的戈登会议的优势在于其学科多样性、关注新的未发表的工作、讨论时间、非正式的氛围以及禁止传播会议记录。