A conductance telemetry system for implant blood pumps

用于植入血泵的电导遥测系统

• 批准号: 6404712
• 负责人: CRAIG W SHERMAN
• 金额: $ 37.67万
• 依托单位: WHALEN BIOMEDICAL, INC
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-05-01 至 2003-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6404712
• 关键词: auxiliary heart prosthesis; biomedical equipment development; circulatory assist; clinical research; electrical conductance; electrical impedance; electrodes; heart electrical activity; human subject; implant; medical implant science; telemetry

DESCRIPTION (provided by applicant): An ideal permanent ventricular assist system (VAS) or total artificial heart (TAH) will not include tubes or wires passing through the skin. This proposal describes development of a telemetry system capable of providing the bi-directional communications between implanted and external components required for safe operation. The ECG signal is a naturally occurring form of telemetry. The voltages sensed by the ECG machine are the result of minute electrical currents generated by the heart flowing through the resistances of the tissues in the thorax. In similar fashion, the Conductance Telemetry System (CTS) transmitter admits minute high frequency currents into tissues via one pair of electrodes producing voltages that can be detected by a remote receiver connected to a second pair of external electrodes. A telemetry system based on this principle will be highly resistant to interruptions of service if issues pertaining to its reliance on chronic skin electrodes can be adequately addressed. The goals of this program are to: 1) develop custom electronic components that make it easy to integrate the CTS into a host system; 2) develop skin electrode systems suitable for use in VAS and TAH patients, and, 3) obtain third party certification of compliance with safety standards. PROPOSED COMMERCIAL APPLICATION: Both the NHLBI and private industry are supporting the devleopment of implantable blood pumps to address the needs of an estimated 30-40,000 patients annually who might benefit from permanent mechanical circulatory support. The proposed device is applicable to virtually all of these systems.

描述（由申请人提供）：理想的永久性心室辅助 系统（VAS）或总人工心脏（TAH）将不包括管子或电线 穿过皮肤。该建议描述了遥测的开发 能够提供植入的双向通信的系统 和安全操作所需的外部组件。 ECG信号是一种天然发生的遥测形式。感觉到电压 通过ECG机器是由微小电流产生的结果 心脏通过胸部组织的阻力流动。在 类似的时尚，电导遥测系统（CTS）发射机承认 微小的高频电流通过一对电极进入组织 产生可以通过连接到一个的远程接收器检测到的电压 第二对外电极。基于此原则的遥测系统 如果与 它可以充分解决其对慢性皮肤电极的依赖。 该计划的目标是：1）开发自定义电子组件 使将CTS集成到主机系统中变得容易； 2）开发皮肤电极 适用于VAS和TAH患者的系统，3）获得第三方 符合安全标准的认证。 拟议的商业应用： NHLBI和私营企业都支持植入血液 满足估计30-40,000名患者的需求的泵，他们可能会受益 来自永久机械循环支持。 提出的设备适用于 几乎所有这些系统。