2001 Gordon Research Conference on Bioenergetics

2001 年戈登生物能量学研究会议

• 批准号: 6367831
• 负责人: William A. Cramer
• 金额: $ 0.7万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-06-15 至 2002-06-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6367831
• 关键词: active transport; bioenergetics; meeting /conference /symposium; membrane biogenesis; membrane proteins; postdoctoral investigator; postgraduate education; protein structure function; structural biology; travel

DESCRIPTION (provided by applicant): The Bioenergetics Gordon Conference is convened biannually and was last held in June, 1999. The larger (ca. 500 person) European Bioenergetics Congress, completed last week, is held in the alternate years. Traditionally, the Bioenergetics GRC has emphasized discussions on mechanisms of electron transport and oxidative phosphorylation, along with the discussions of the biomedical implications for mitochondrial myopathies and aging. However, as the majority of the first high resolution structures of integral membrane proteins were obtained from energy-transducing membranes, this Conference has become a major platform for discussions of integral membrane protein biochemistry. Structure-based discussion of mechanism involving integral membrane proteins has now become a basic theme of the Bioenergetics GRC, and contributions in this cutting-edge area are a major criteria in the planning and organization of the sessions. Thus, the determination in the last year of the high resolution (1.55 A) structure of bacteriorhodopsin, the highest resolution membrane protein structure, along with high resolution structures of halorhodopsin and rhodopsin, created a wonderful opportunity for a comparative presentation and discussion of the structures and evolution of the rhodopsin family. The present program will also have major sessions on Active Transport and Biogenesis. The special features of informality and spontaneity of Gordon Conferences allow the possibility of in-depth discussions of fundamental questions. To further stimulate such discussions, to the extent that it is feasible, this Conference is being organized around conceptual themes rather than focused on individual proteins or experimental systems. This is a bit of an experiment, but I believe it will be interesting. The major use of the funds requested in this application is to support the attendance at this conference of "young" people, graduate students and postdoctorals. Forty-six students and postdocs, out of a total of 145 in attendance, came to the last Conference. The research discoveries, relevance of spectoscopic methods, and quantitative analysis of integral membrane proteins make it essential to educate, and inform the young researchers interested in this field, who will form its next generation. The Bioenergetics GRC is a wonderfully inspiring venue for these purposes. Of course, the ideas and studies contributed by the younger folks are also inspirational to the rest of us.

描述（由申请人提供）：生物能量戈登会议是 一年一度召集，最后一次于1999年6月举行。较大（大约500 ）上周完成的欧洲生物能源大会在替代年份举行。传统上，生物能力GRC强调 讨论电子传输机制和氧化磷酸化的讨论， 以及对线粒体生物医学含义的讨论 肌病和衰老。但是，作为第一个高分辨率的大多数 通过能量转换获得整体膜蛋白的结构 膜，这次会议已成为讨论的主要平台 整体膜蛋白生物化学。基于结构的机制讨论 涉及整体膜蛋白现在已成为该蛋白的基本主题 生物能源GRC和在这个尖端地区的贡献是主要的 会议计划和组织的标准。因此， 高分辨率（1.55 a）结构的最后一年的确定 细菌视紫红质，最高分辨率的膜蛋白结构，沿 具有甲状腺素和视紫红质的高分辨率结构，创造了一个 对比较演讲和讨论的绝佳机会 视紫红质家族的结构和进化。目前的程序也将 在主动运输和生物发生方面有主要会议。 戈登会议的非正式和自发性的特殊特征允许 深入讨论基本问题的可能性。进一步 这次会议刺激这种讨论，以至于它是可行的 正在围绕概念主题组织，而不是专注于个人 蛋白质或实验系统。这是一个实验，但我相信 这会很有趣。 本申请中要求的资金的主要用途是支持 参加这次“年轻”人，研究生和 博士后。 46名学生和博士后，总共145个 出席，参加了最后一次会议。研究发现，相关性 光谱方法和整体膜蛋白的定量分析 使教育和通知感兴趣的年轻研究人员至关重要 这个领域将构成下一代。生物能力GRC是 出于这些目的，令人振奋的场地。当然，想法和 年轻人贡献的研究也对其余的 我们。