HEAD CONTROL MECHANISMS DURING VOLUNTARY TRUNK MOVEMENTS

躯干自愿运动期间的头部控制机制

• 批准号: 6363930
• 负责人: Timothy C Hain
• 金额: $ 14.06万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-03-01 至 2003-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6363930
• 关键词: balance; brain disorders; clinical research; computer simulation; electromyography; functional ability; head movements; human subject; neck; neuromuscular function; proprioception /kinesthesia; psychomotor function; sensorimotor system; vestibular pathway; vestibuloocular reflex

The aim of this project is to determine how intentional mechanisms contribute to head stabilization in the pitch (sagittal) plane during voluntary trunk movements in persons with intact and bilaterally impaired vestibular (BVL) systems. One set of studies will quantify the contributions made by intentional mechanisms beyond reflex and mechanical processes. A second set of studies will evaluate what subtypes of intentional strategies are used to stabilize the head under different conditions. Empirical and computer modeling approaches will test the hypotheses that intentional mechanisms contribute significantly to head stabilization in the BVL as well as intact subject, and that these groups use different subtypes of strategies to stabilize their heads. In the empirical studies, subjects will sit on a sled that can translate in the anterior-posterior direction. They will voluntarily control translation of the sled by a hand-held joystick, and have some sled motions imposed on them. The sled translations generate forces that destabilize the head in the pitch plane. Analyses of head motion and torques and of electromyographic activity in the neck and trunk muscles will reveal how well subjects counteract the head-destabilizing forces during sled translation. The data also will reveal whether subjects stabilize their heads by avoiding the disturbance (reducing trunk subjects motion), anticipating and predictively cancelling the disturbance, by stiffening their neck through muscle cocontraction, or by relying on reflexes and passive mechanics. An analytical model of the head-neck control system will be used to run simulations that will determine how much intentional mechanisms contribute to head stabilization, and that will establish how combinations of intentional, mechanical and reflex strategies could work together to stabilize the head. This project is the first to evaluate intentional head-stabilizing mechanisms during voluntary trunk movements. The project also will add to basic knowledge of head control mechanisms by evaluating intentional processes during voluntary movements that are similar to activities of daily life, which generally involve voluntary rather than imposed motion of the trunk. The comparison of intact and BVL populations will elucidate why some persons with BVL recover relatively high functional levels, and others do not.

该项目的目的是确定有意的机制 在音高（矢状）平面的头部稳定 完整和双侧的人的自愿行李箱运动 前庭（BVL）系统受损。 一组研究将量化 通过反射和反射之外的故意机制做出的贡献 机械过程。 第二组研究将评估什么 有意策略的亚型用于稳定下面的头部 不同的条件。 经验和计算机建模方法将 测试有意机制显着贡献的假设 在BVL和完整的主题中进行稳定，并 这些小组使用不同的策略亚型来稳定其 头。 在经验研究中，受试者将坐在可以 沿前后方向翻译。 他们将自愿 控制手持操纵杆对雪橇的翻译，并有一些 雪橇动议对他们施加。 雪橇翻译产生力 这使头顶平面上的头部稳定。 头运动分析 和颈部和躯干中的肌电图和肌电运动活性 肌肉将揭示受试者如何应对戴头脑的效果 雪橇翻译过程中的力。 数据还将揭示是否 受试者通过避免干扰来稳定头部（减少 中继主题运动），预期和预测取消 干扰，通过肌肉授予的颈部僵硬或 通过依靠反射和被动力学。 一个分析模型 头颈控制系统将用于运行模拟 确定有多少故意机制有助于头部 稳定，这将确定有意的组合， 机械和反射策略可以共同稳定 头。 该项目是第一个评估故意稳定的项目 自愿行李箱运动中的机制。 该项目还将添加 通过评估有意的头部控制机制的基本知识 自愿运动期间的过程类似于 日常生活，通常涉及自愿而不是强加运动 树干。 完整和BVL种群的比较将 阐明某些BVL的人恢复功能较高的原因 级别，其他人则没有。