ADOLESCENT MEDICINE TRIAL NETWORK FOR HIV/AIDS

艾滋病毒/艾滋病青少年药物试验网络

• 批准号: 6331772
• 负责人: Ligia Peralta
• 金额: $ 151.22万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-16 至 2006-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6331772
• 关键词: AIDS; AIDS /HIV diagnosis; AIDS /HIV test; AIDS education /prevention; HIV infections; adolescence (12-20); clinical trials; cooperative study; counseling; disease /disorder proneness /risk; health behavior; health care referral /consultation; human subject; longitudinal human study; medical outreach /case finding; patient oriented research; pediatric AIDS; sex behavior; social service; substance abuse related disorder; urban area; young adult human (21-34); AIDS; AIDS /HIV diagnosis; AIDS /HIV test; AIDS education /prevention; HIV infections; adolescence (12-20); clinical trials; cooperative study; counseling; disease /disorder proneness /risk; health behavior; health care referral /consultation; human subject; longitudinal human study; medical outreach /case finding; patient oriented research; pediatric AIDS; sex behavior; social service; substance abuse related disorder; urban area; young adult human (21-34)

DESCRIPTION: (provided by applicant): The University of Maryland STAR TRACK Adolescent HIV Program (STAR TRACK Program) is a clinical and research unit with significant experience in the areas of adolescent HIV research. STAR TRACK is the only adolescent exclusive HIV service in the state of Maryland and has a comprehensive "one stop shopping" model of care, a state wide community outreach program, an HIV early identification program through an adolescent specific HIV counseling and testing unit, and a Youth Care Network that serves as referral network for both HIV+ and HIV-youths. Our program has been one of 15 sites of the Adolescent HIV/AIDS Research Network since 1994 with a successful track record of recruitment, retention, site performance, quality assurance. Our PI, study coordinators, and Youth Community Advisory Board member have productively participated in and contributed towards the AMHARN mission and its goals. Our program has extensive experience in the recruitment and retention of HIV+ and HIV-adolescents in clinical care and research, and an active caseload of 105 HIV+ youths (many of whom have research experience) and 125 HIV-youths. STAR TRACK has strong clinical and research collaborations with other clinical sites for a total of 180 HIV infected young people under the age of 24. Our program has highly experienced adolescent researchers and study coordinators as well as basic and clinical researchers of the Division of Pediatric Immunology and the Institute of Human Virology of the University of Maryland. These investigators have an extensive track record of leadership in multicenter collaborative trials. The tight interface between community outreach, early identification of HIV, linkage to care and research, and comprehensive primary and subspecialty care, intrinsic to STAR TRACK?s structure, facilitates the major goals of the ATN. These relationships also provide a great structure to expand subject recruitment. This application details the current clinical and research capacity of the Adolescent Medicine Trial Unit (AMTU) to conduct research protocols related to the primary, secondary and tertiary prevention of HIV. High-risk populations available for this research include high-risk sexual minority and heterosexual youths, as well as incarcerated and substance abusing youths. In addition, it includes youths in transitional housing situation and school dropouts. Furthermore, the strong collaboration with an experienced laboratory, database manager and other University of Maryland scientists with expertise in HIV clinical trials and vaccine development provides an optimal environment for enriching the basic science and laboratory-based agenda of the ATN.

描述：（由申请人提供）：马里兰大学星际曲目 青春期艾滋病毒计划（Star Track Program）是临床和研究部门 在青少年艾滋病毒研究领域具有丰富的经验。星星 赛道是马里兰州唯一的青少年独家艾滋病毒服务 并具有全面的“一站式购物”护理模型，这是一个全州范围的 社区外展计划，艾滋病毒早期身份证明计划 青少年特定的艾滋病毒咨询和测试部门以及青年护理网络 这是HIV+和HIV-Youths的推荐网络。我们的计划有 自1994年以来一直是青少年艾滋病毒/艾滋病研究网络的15个地点之一 凭借成功的招聘，保留，现场性能的记录， 质量保证。我们的PI，学习协调员和青年社区咨询 董事会成员有效地参与了 Amharn的使命及其目标。我们的计划在 在临床护理中招募和保留HIV+和HIV-ADECENTENS 研究，以及105名HIV+青年的活跃案件（其中许多 研究经验）和125个HIV-Youths。星条道具有强大的临床和 与其他临床部位的研究合作，共有180名艾滋病毒 感染了24岁以下的年轻人。我们的计划经验丰富 青少年研究人员和研究协调员以及基本和临床 小儿免疫学和人类研究所的研究人员 马里兰大学病毒学。这些调查人员有广泛的 多中心协作试验中领导力的记录。紧 社区外展，早期识别艾滋病毒，与与 护理和研究，以及全面的初级和专业护理，内在的 为了播放轨道的结构，可以促进ATN的主要目标。这些 关系还为扩大主题招聘提供了一个很好的结构。 此应用程序详细介绍了当前的临床和研究能力 青少年医学试验部（AMTU）进行与 艾滋病毒的主要，二级和第三级预防。高风险人群 该研究可用于高风险性少数群体和异性恋 年轻人以及被监禁和滥用青年的物质。另外，它 包括过渡住房情况和学校辍学的年轻人。 此外，与经验丰富的实验室数据库的强大合作 经理和其他具有艾滋病毒专业知识的马里兰大学科学家 临床试验和疫苗开发为 丰富了ATN的基础科学和实验室议程。