OCULAR HYPERTENSION TREATMENT STUDY (OHTS)

眼压过高治疗研究 (OHTS)

• 批准号: 6342632
• 负责人: ROBERT N WEINREB
• 金额: $ 15.05万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-01-01 至 2003-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6342632
• 关键词: African American; beta antiadrenergic agent; carbachol; chemoprevention; clinical trials; cooperative study; disease /disorder proneness /risk; dosage; drug administration routes; drug adverse effect; early diagnosis; epinephrine; eye disorder chemotherapy; eye fundus photography; eye pharmacology; glaucoma; glaucoma test; human subject; human therapy evaluation; intraocular pressure; longitudinal human study; mass screening; medical complication; miotic; optic disk; pilocarpine; prognosis; statistics /biometry; therapy compliance; vision disorders; visual fields

DESCRIPTION (Investigator's Abstract) "This is an application to become a participating Clinical Center in the Ocular Hypertension Treatment Study (OHTS). The complete details of the OHTS rationale, design, and methods are contained in the OHTS Manual of Procedures. This proposal provides complete documentation of the ability of the University of California, San Diego, to screen large numbers of ocular hypertensive patients and to enroll at least 50 eligible patients over a 24-month period. Rigby Slight, M.D., backup for the Principal Investigator, is an Associate Clinical Professor of Ophthalmology and a full time glaucoma specialist in private practice in the area who will refer or follow patients screened for enrollment and randomization to treatment in the OHTS clinical trial. Documentation is provided of the capabilities of the proposed investigators and their staff for the performance of the study in accord with the details of the OHTS Manual of Procedures, the nature and extent of their commitment to the University of California, San Diego."

描述（研究者的摘要） “这是成为参与临床中心的申请 眼高血压治疗研究（OHTS）。 完整的细节 OHTS理由，设计和方法包含在OHTS手册中 程序。 该建议提供了完整的文档 加利福尼亚大学圣地亚哥分校，以筛选大量眼 高血压患者，并至少在A上注册50名合格患者 24个月。 Rigby Little，医学博士，校长的备份 研究者是眼科副临床教授和 该地区私人执业的全职青光眼专家 参考或关注筛查的患者进行入学和随机分组 在OHTS临床试验中进行治疗。 提供了拟议调查员的功能的文件 以及他们的员工在研究表演的情况下符合详细信息 OHTS手册，其承诺的性质和程度 到加州大学圣地亚哥分校。”