Ophthalmology and Visual Sciences Career Development K12 Program

眼科和视觉科学职业发展 K12 计划

• 批准号: 10676982
• 负责人: ROBERT N WEINREB
• 金额: $ 49.34万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-04-01 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10676982
• 关键词: Appointment; Area; Artificial Intelligence; Award; Basic Science; Biomedical Engineering; Childhood; Clinical; Clinical Sciences; Department chair; Education; Educational Curriculum; Ethics; Eye; Fellowship; Funding; Genomics; Glaucoma; Goals; Grant; Individual; Informatics; Institution; K-Series Research Career Programs; Lead; Leadership; Mentored Clinical Scientist Development Program; Mentors; Minority; Ophthalmology; Preparation; Proteomics; Research; Residencies; Retina; Scientist; Structure; Training; United States National Institutes of Health; Woman; Writing; career; career development; clinically relevant; human subject; next generation; programs; recruit; responsible research conduct; skills; statistics; stem cell biology; vision science; visual neuroscience

PROJECT SUMMARY / ABSTRACT The overall objective of the NEI Mentored Clinical Scientist Development Program Award at UCSD is to develop outstanding clinician scientists to successfully compete for NIH grants and emerge as leaders within academic ophthalmology. Through this institutional career development award, we will continue to mentor clinician scientists toward independent academic appointments in ophthalmology. Since 1991, the UC San Diego Shiley Eye Institute has excelled in mentoring the career development of clinician scientists throughout ophthalmology. Many of these individuals now have successful research and clinical careers around the world; they include Department Chairs, Division Chiefs, and impactful academicians. With continued funding, we will amplify these strengths through a structured program of mentoring, research, and education to identify and mentor the next generation of academic clinician scientists, across all subspecialty areas of ophthalmology. With an emphasis on recruiting strong applications from women and minority applicants, Scholars will be selected each year after their completion of a post-residency clinical fellowship in ophthalmology. The Scholar will undertake these activities in the area of basic and/or clinical sciences appropriate to their scientific focus, and by partnering with mentor(s) to facilitate career development. Each Scholar will be trained in clinically relevant research, statistics, scientific writing, grant preparation, ethics, leadership, and the responsible conduct of research. Additional aspects of the curriculum of each Scholar will be individualized by the Program Director (PI), Research Directors, Education Director, Executive Committee, Mentoring Group, and lead mentor based upon the Scholar's selected primary research track and his/her skills, background, and career goals. Each Scholar will create an original research program and through this Award develop an independent academic career. We propose six primary research tracks: (1) Visual Neuroscience, (2) Genomics and Proteomics, (3) Bioengineering, (4) Stem Cell Biology, (5) Artificial Intelligence and Informatics, and (6) Clinical (human subjects) Research. In the first K12 funding period, we trained and recruited four clinician scientists in the subspecialty areas of retina (2), glaucoma (1), and pediatric ophthalmology (1). Two of these Scholars already have received NIH K08 awards, and the other two have submitted K08 proposals that are under consideration.

项目摘要 /摘要 UCSD的NEI指导临床科学家发展计划奖的总体目标是开发 杰出的临床医生科学家成功竞争NIH赠款，并成为学术领导者 眼科。通过这个机构职业发展奖，我们将继续指导临床医生 科学家进行眼科独立学术任命。自1991年以来，加州大学圣地亚哥分校 Eye Institute在整个眼科研究中都表现出色，以指导临床科学家的职业发展。 这些人中的许多人现在在世界各地都有成功的研究和临床职业。它们包括 部门主席，部门负责人和有影响力的院士。凭借持续的资金，我们将扩大这些 通过结构化的指导，研究和教育计划的优势，以识别和指导下一个 学术临床医生科学家的产生，在眼科的所有亚科领域。 重点是招募妇女和少数民族申请人的强大申请，学者将是 在完成居住后临床奖学金后，每年选择。学者 将在适合其科学重点的基础和/或临床科学领域进行这些活动， 并与导师合作以促进职业发展。每个学者将在临床上接受培训 相关研究，统计，科学写作，赠款准备，道德，领导和负责任的行为 研究。每个学者课程的其他方面将由计划主任个性化 （PI），研究主管，教育总监，执行委员会，指导小组和主要导师 根据学者选择的主要研究轨道以及他/她的技能，背景和职业目标。每个 学者将创建一个原始的研究计划，并通过该奖项发展独立的学术 职业。 我们提出了六个主要研究轨道：（1）视觉神经科学，（2）基因组学和蛋白质组学，（3） 生物工程，（4）干细胞生物学，（5）人工智能和信息学，以及（6）临床（人类受试者） 研究。 在第一个K12资助期间，我们在视网膜的亚科培训和招募了四名临床医生 （2），青光眼（1）和小儿眼科（1）。这些学者中有两个已经收到NIH K08 奖项，另外两个提交了正在考虑的K08提案。

项目成果

Identification of the genetic determinants responsible for retinal degeneration in families of Mexican descent.

• DOI: 10.1080/13816810.2017.1373830
• 发表时间: 2018-01
• 期刊: Ophthalmic genetics
• 影响因子: 1.2
• 作者: Villanueva A;Biswas P;Kishaba K;Suk J;Tadimeti K;Raghavendra PB;Nadeau K;Lamontagne B;Busque L;Geoffroy S;Mongrain I;Asselin G;Provost S;Dubé MP;Nudleman E;Ayyagari R
• 通讯作者: Ayyagari R

COMPARISON OF 3 MM × 3 MM VERSUS 6 MM × 6 MM OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY SCAN SIZES IN THE EVALUATION OF NON-PROLIFERATIVE DIABETIC RETINOPATHY.

• DOI: 10.1097/iae.0000000000001951
• 发表时间: 2019-03
• 期刊: Retina (Philadelphia, Pa.)
• 作者: Ho J;Dans K;You Q;Nudleman ED;Freeman WR
• 通讯作者: Freeman WR

Large-scale assessment of needs in low vision individuals using the Aira assistive technology.

使用 Aira 辅助技术对低视力人群的需求进行大规模评估。

• DOI: 10.2147/opth.s215658
• 发表时间: 2019
• 期刊: Clinical ophthalmology (Auckland, N.Z.)
• 作者: Nguyen,BrianJ;Chen,WilliamS;Chen,AllisonJ;Utt,Andrew;Hill,Emily;Apgar,Ryan;Chao,DanielL
• 通讯作者: Chao,DanielL

Pseudobleb of silicone oil-related progressive staphylomatous scleral ectasia.

硅油相关的进行性葡萄肿性巩膜扩张的假泡。

• DOI: 10.1016/j.jfo.2022.07.026
• 发表时间: 2023
• 期刊: Journal francais d'ophtalmologie
• 作者: Toomey,CB;Akpek,E;Breazzano,MP
• 通讯作者: Breazzano,MP

A Randomized Controlled Trial Comparing Subconjunctival Injection to Direct Scleral Application of Mitomycin C in Trabeculectomy.

• DOI: 10.1016/j.ajo.2020.07.002
• 发表时间: 2020-12
• 期刊: American journal of ophthalmology
• 影响因子: 4.2
• 作者: Do JL;Xu BY;Wong B;Camp A;Ngai P;Long C;Proudfoot J;Moghimi S;Yan D;Welsbie DS;Weinreb RN
• 通讯作者: Weinreb RN