STFC Cancer Diagnosis Network+

STFC癌症诊断网络

基本信息

批准号：
ST/S005404/1
负责人：
Laura Joanne Harkness-Brennan
金额：
$ 62.05万
依托单位：
University of Liverpool
依托单位国家：
英国
项目类别：
Research Grant
财政年份：
2019
资助国家：
英国
起止时间：
2019 至无数据
项目状态：
未结题

来源：
https://gtr.ukri.org/projects?ref=ST%2FS005404%2F1
关键词：
STFC Cancer Diagnosis Network+

项目摘要

This proposal seeks to establish a multidisciplinary community to address challenges in the diagnosis of cancer, which is one of the most important societal and economic global challenges of this century. Cancer accounts for 1 in every 6 deaths worldwide, which makes it the second leading cause of death globally. In addition to the devastating impact of this disease on patients and their families, the total annual global economic cost of cancer is estimated to be approximately £1 trillion. The challenge will become even more prevalent in our ageing society, since the incidence of cancer rises significantly with age, whilst cellular repair mechanisms also become less effective. Reducing cancer mortality rates in our ageing global population could be achieved by earlier diagnosis and more accurate staging of disease. The Network+ community will develop technologies and techniques that aim to improve patient quality of life, increase the chance of patient survival and reduce associated cancer services costs. The Network+ will focus on four themes of (1) early diagnosis, (2) precision and quantitative imaging, (3) multimodal techniques and (4) data science techniques applied to imaging and bioinformatics. The expertise developed through the core STFC science programmes that are particularly relevant to these topics are the development of high resolution and high sensitivity detectors, multispectral detectors, algorithms for image analysis and data mining techniques. The network+ will host multidisciplinary challenge-led workshops and provide funding for approximately 16 scoping studies, 5 to 10 proof of concept projects and 2 co-funded PhD studentships. It will also develop the research capacity of early career researchers through travel awards, discipline-hopping placements and training. In addition, position papers and fact sheets will be produced. The network will actively engage with external partners to build membership. The results from the funded projects will be disseminated to members by newsletters, a website and at an end of network conference, which will also be a forum to discuss potential future collaborative opportunities. The website will also be used to showcase events to all stakeholders.

该提案旨在建立一个多学科社区来应对癌症诊断方面的挑战，癌症是本世纪最重要的社会和经济全球挑战之一，全球每 6 名死亡中就有 1 人死于癌症，这使其成为第二大原因。除了这种疾病对患者及其家人造成的毁灭性影响外，癌症每年造成的全球经济损失估计约为 1 万亿英镑，因为这一挑战在我们的老龄化社会中将变得更加普遍。癌症发病率随着年龄的增长而显着上升，而细胞修复机制通过早期诊断和更准确的疾病分期，可以降低全球老龄化人口中的癌症死亡率。Network+ 社区将开发旨在改善患者生活质量、增加患者生存机会的技术和方法。 Network+ 将重点关注四个主题：(1) 早期诊断、(2) 精确和定量成像、(3) 多模态技术和 (4) 应用于成像和生物信息学的数据科学技术。通过 STFC 核心科学与这些主题特别相关的计划包括开发高分辨率和高灵敏度探测器、多光谱探测器、图像分析算法和数据挖掘技术。 Network+ 将举办以多学科挑战为主导的研讨会，并为大约 16 项范围研究、5 项提供资金。它还将通过旅行奖励、跨学科安置和培训来培养早期职业研究人员的研究能力。该网络将积极与外部合作伙伴合作，以建立会员资格，并将通过新闻通讯、网站和网络会议结束时向成员传播，该会议也将成为讨论未来潜在合作机会的论坛。该网站还将用于向所有利益相关者展示活动。