MECHANISM OF PESTICIDE BY SOIL ORGANIC MATTER

土壤有机质杀虫机理

• 批准号: 6309161
• 负责人: WILLIAM BLEAM
• 金额: $ 0.75万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-04-15 至 2005-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6309161
• 关键词: biological products; biomedical resource; nuclear magnetic resonance spectroscopy; plants

Atrazine is an important agriculture herbicide for weed control in the cultivation of corn and sorghum. This experiment is to study the cooperative hydrogen bonding and hydrogen bonding potential of CF3-labeled atrazine. A nonlinear optimization procedure is developed to find the dimerization constants of atrazine from the NMR chemical shifts of four of its NH protons. The NH protons identify four active sites which interact pairwise by cooperative association to form a total of 10 hydrogen-bonded dimers. Each active site is assumed to have a partial dimerization constant related its chemical potential, and the partial constants are used to develop equations which fit the chemical shift data to a cooperative dimerization model. The partial dimerization constants are multiplied together pairwise to obtain the dimerization constant for each of the 10 atrazine dimers. We will run 19F-NMR (5mm Tube) of CF3-atrazine in CCl4 containing the following organic complexing agents at concentrations from 0.71 mM to 4.5 mM: acetic acid (HOAC), pyrrolidine (CNH), cyclopentanone (CP), pyrrole (PYRR), dimethyl sulfoxide (DMSO), acetone (ACE), phenol (PHEN), ethanol (EtOH), and methyl acetate (MEAC).

阿特拉津是重要的农业除草剂，用于杂草控制 玉米和高粱的种植。 该实验是研究 合作氢键和氢键的氢键 CF3标记的阿特拉津。 开发了非线性优化程序 从NMR Chemical中找到Atrazine的二聚化常数 其四个NH质子的转移。 NH质子识别四个活动 由合作协会成对相互作用以形成一个的站点 总共10个氢键二聚体。 假定每个活动站点 具有部分二聚体常数有关其化学潜力的关系， 部分常数用于开发适合 化学转移数据到合作二聚化模型。 部分 将二聚化常数成对乘以 10个阿atrazine二聚体中的每个二聚体常数。 我们将运行 CCL4中的CF3-芳津的19F-NMR（5mm管）包含以下 浓度从0.71 mm至4.5 mm的有机络合剂： 乙酸（HOAC），吡咯烷（CNH），环戊酮（CP），吡咯 （pyrr），二甲基亚氧化二甲基（DMSO），丙酮（ACE），苯酚（PEN），， 乙醇（ETOH）和乙酸甲醇（MEAC）。