GENETIC EPIDEMIOL OF PERIODONTAL DISEASE: DENTAL STUDIES & FAMILIAL AGGREGATION

牙周病的遗传流行病：牙科研究

• 批准号: 6348124
• 负责人: JAMES D BECK
• 金额: $ 0.38万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-01 至 2001-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6348124
• 关键词: biomedical resource; child (0-11); epidemiology; female; genetics; human subject; male; oral pharyngeal

The object of this study is the assessment of familial aggregation of outcomes measuring periodontal disease in a population-based family study in the Piedmont area of North Carolina. The study sample includes members of nuclear families ascertained through individuals studied as part of a population-based epidemiologic study of elder North Carolinians, regardless of periodontal status. Clinical, behavioral, and immunological measures were obtained for study. In a subset of these persons, who were found to have severe periodontal disease, extended family structures were sampled. Analyses to date provide evidence of significant levels of familial aggregation.

这项研究的目的是对家族聚集的评估 测量基于人群家族的牙周疾病的结果 在北卡罗来纳州皮埃蒙特地区的研究。 研究样本 包括通过个人确定的核心家庭成员 作为基于人群的老年流行病学研究的一部分 北卡罗莱纳州，无论牙周地位如何。 临床， 获得了行为和免疫学措施进行研究。 在 这些人的子集，被发现有严重的牙周 疾病，大家庭结构进行了采样。 分析迄今为止 提供大量家庭聚集的证据。