ALCOHOL RESEARCH--RISK AND PROTECTION IN ETHNIC GROUPS

酒精研究——少数民族的风险和保护

• 批准号: 6371228
• 负责人: TAMARA L WALL
• 金额: $ 9.48万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-08-01 至 2003-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6371228
• 关键词: Asian Americans; Native Americans; alcoholism /alcohol abuse; clinical research; disease /disorder proneness /risk; gene environment interaction; human subject; longitudinal human study; racial /ethnic difference; social psychology

The University of California, San Diego (UCSD), Department of Psychiatry hereby applies on behalf of Tamara L. Wall for an Independent Scientist Award (KO2) from the National Institute on Alcohol Abuse and Alcoholism (NIAAA). The overall aim of the proposed Research Career Award is to free the candidate from clinical and administrative duties so that she may devote nearly full-time to continue and develop further her research evaluating risk and protective factors for alcohol involvement within different ethnic groups. Asian Americans and Native American Indians vary greatly with respect to patterns, prevalences, and consequences of alcohol use. These differences are hypothesized to result from a combination of biological and psychosocial factors. This application has two overall goals: 1) to complete two projects currently funded by NIAAA focused on understanding the effects of genetic influences on response to alcohol in Asian Americans and Native American Indians; and 2) to expand upon these studies by evaluating the combined contributions of biological and psychosocial influences on alcohol drinking patterns and problems within these ethnic groups using cross-sectional, and eventually longitudinal, data. Results obtained from these studies will provide important information regarding the complex relationship between biological and environmental aspects of vulnerability to, and protection from, alcoholism. The candidate has made a strong commitment to alcohol-related research. Activities for her continued career development will include: 1) intensive new training with leading research scientists in the importance of psychosocial factors in developmental models of alcohol use and alcohol problems, statistical modeling techniques, and longitudinal research design; 2) coursework on advanced structural modeling and the responsible conduct of research; and 3) participation in department seminars and scientific meetings.

加州大学圣地亚哥分校（UCSD），精神病学系 特此代表塔玛拉·沃尔（Tamara L. Wall）为独立科学家 美国国家酒精滥用和酒精中毒研究所的奖项（KO2） （NIAAA）。 拟议研究职业奖的总体目的是 将候选人免于临床和行政职责，以便她 可能几乎全职致力于继续并进一步发展她的研究 评估风险和保护因素，以供酒精参与 不同的种族。 亚裔美国人和美洲印第安人 在模式，流行率和后果方面差异很大 饮酒。 这些差异被认为是由 生物学和社会心理因素的结合。 该应用程序有两个总体目标：1）完成两个项目 目前由NIAAA资助的重点是了解 亚裔美国人和当地人对酒精反应的遗传影响 美洲印第安人； 2）通过评估这些研究来扩展这些研究 生物学和社会心理影响的综合贡献对 这些种族中的饮酒方式和问题 横截面，最终是纵向的数据。 获得的结果 从这些研究中将提供有关 生物学和环境方面之间的复杂关系 对酒精中毒的脆弱性和保护。 候选人有 对与酒精有关的研究做出了坚定的承诺。她的活动 持续的职业发展将包括：1）强化新培训 与领先的研究科学家有关社会心理的重要性 酒精使用和酒精问题的发展模型的因素， 统计建模技术和纵向研究设计； 2） 高级结构建模和负责任的课程 研究； 3）参加部门研讨会和科学 会议。