CEFTRIAXONE AND DOXYCYCLINE IN PATIENTS WITH SERONEGATIVE CHRONIC LYME DISEASE

头孢曲松和多西环素治疗血清阴性慢性莱姆病患者

• 批准号: 6304538
• 负责人: Mark S Klempner
• 金额: $ 4.27万
• 依托单位: TUFTS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-12-01 至 2001-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6304538
• 关键词: Lyme disease; antibacterial agents; case history; cephalosporins; chronic disease /disorder; clinical research; clinical trials; drug screening /evaluation; human subject; human therapy evaluation; microorganism disease chemotherapy; neuropsychological tests; quality of life; tetracyclines

These studies will explore treatment strategies for chronic lyme disease and will be conducted at two centers, New England Medical Center/Tufts University School of Medicine and Westchester County Medical Center affiliated with New York Medical College. The coordinating center, and the central laboratory facility will be at New England Medical Center. Investigators will perform an initial assessment of each patient for collection of demographic data, a history of exposure to ticks in geographic regions with endemic B. burgdorferi infection. Treatment interventions and clinical endpoints will be assessed.

这些研究将探讨慢性莱姆病的治疗策略，并将在两个中心进行：新英格兰医学中心/塔夫茨大学医学院和纽约医学院附属威彻斯特县医学中心。 协调中心和中央实验室设施将设在新英格兰医学中心。研究人员将对每位患者进行初步评估，以收集人口统计数据、伯氏疏螺旋体感染流行地区的蜱接触史。 将评估治疗干预和临床终点。