WARPRC BSL 2/3 RENOVATION AND EQUIPMENT

WARPRC BSL 2/3 翻新和设备

• 批准号: 2695486
• 负责人: William Randall Morton
• 金额: $ 69.73万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-15 至 2001-09-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2695486
• 关键词: animal care; animal colony; biomedical equipment purchase; biomedical resource; building /facility design /renovation; germ free condition

The Washington Regional Primate Research Center (WaRPRC) has a long and successful history of biomedical-related research utilizing non-human primates. The long-term goal of the WaRPRC is to optimize support for significant, highly-relevant biomedical research utilizing non-human primates. The short-term goal of the WaRPRC is to increase the available BSL2/3 housing to optimally support current research protocols and future grant projects requiring BSL2/3 housing facilities. To meet this end, the WaRPRC has developed this grant application to support expansion into an almost new, state-of-the-art vivarium formerly owned by the Bristol-Myers Squibb Pharmaceutical Company (BMS). Expansion into this facility would allow the addition of approximately 540 cage spaces available for non- human primates house in BSL2/3 level conditions, thereby more than doubling the cage space available at the WaRPRC for highly relevant biomedical research projects, such as AIDS-related investigation into vaccine development, pathogenesis and therapeutics. The Specific Aims of this application are: 1) to convert the BMS vivarium facility to optimized, standard BSL2/3 housing for non-human primates and 2) to expand the capabilities of the WaRPRC to support additional areas of research, including maternal-fetal and neurobehavioral programs. This application seek support for limited modification of the facility and purchase of equipment for the former BMS vivarium for conversion into a BSL2/3 housing area suitable for non-human primates. This conversion will allow a significant improvement in support of current BSL2/3 AIDS-related projects, as well as expansion of similar projects in the future.

华盛顿地区灵长类动物研究中心 (WaRPRC) 拥有悠久的历史 利用非人类生物医学相关研究的成功历史 灵长类动物。 WaRPRC 的长期目标是优化对 利用非人类进行重要的、高度相关的生物医学研究 灵长类动物。 WaRPRC 的短期目标是增加可用的 BSL2/3 外壳可最佳支持当前的研究协议和未来 需要 BSL2/3 住房设施的拨款项目。为了达到这个目的， WaRPRC 开发了这项拨款申请，以支持扩展到 几乎全新、最先进的动物园，原属于百时美施贵宝公司 施贵宝制药公司（BMS）。扩建该设施将 允许增加大约 540 个笼子空间可用于非 人类灵长类动物生活在 BSL2/3 水平条件下，因此超过 将 WaRPRC 的可用笼子空间加倍，以实现高度相关 生物医学研究项目，例如与艾滋病相关的调查 疫苗开发、发病机制和治疗。具体目标 该应用程序是： 1) 将 BMS 动物饲养场设施转换为 适用于非人类灵长类动物的优化标准 BSL2/3 住房以及 2) 扩展 WaRPRC 支持其他研究领域的能力， 包括母胎和神经行为项目。这个应用程序 寻求对设施的有限改造和购买的支持 用于将前 BMS 饲养场转换为 BSL2/3 外壳的设备 适合非人类灵长类动物居住的区域。这种转换将允许 对当前 BSL2/3 艾滋病相关支持的显着改进 项目，以及未来类似项目的扩展。