NEURAL BASIS OF RECOVERY FROM EARLY CORTICAL BLINDNESS

早期皮质失明恢复的神经基础

• 批准号: 6277518
• 负责人: HILLARY R RODMAN
• 金额: $ 4.16万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-05-01 至 1999-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6277518
• 关键词: Mammalia; Primates; animal tissue; growth /development; injury; nervous system; psychology

Damage to primary visual cortex (V1) is an important cause of blindness in both children and adults. However, far better recovery follows when the damage takes place early in life. The aim of this project was to examine the existence of a specific brain pathway in infant but not adult primates which could help account for the better recovery seen after early damage. Data collected this year do not support such a pathway, but point instead to a role for the pulvinar in the improved recovery. Moreover, the data suggest that the protein calbindin is important in the survival of cells in the visual system after damage to V1. of Prevent Blindness America

损害主要视觉皮层（V1）是 儿童和成人的失明。 但是，康复要好得多 何时损害发生在生命的早期。 这个目的 项目是检查在 婴儿但不是成年灵长类动物，这可以帮助您更好地解释 早期伤害后看到的恢复。 今年收集的数据没有 支持这样的途径，但要指出Pulvinar的角色 在改善的恢复中。 此外，数据表明蛋白质 Calbindin在视觉系统中细胞的存活中很重要 损坏V1后。 防止失明美国