TAXONOMY AND DIAGNOSIS OF ADOLESCENT ALCOHOL USE DISORDERS

青少年酒精使用障碍的分类和诊断

• 批准号: 6267115
• 负责人: CHRISTOPHER S MARTIN
• 金额: $ 21.59万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6267115
• 关键词: adolescence (12-20); alcoholic beverage consumption; alcoholism /alcohol abuse; behavior prediction; clinical research; diagnosis quality /standard; disease /disorder classification; drug abuse; human subject; longitudinal human study; mental disorder diagnosis; psychometrics; relapse /recurrence

Understanding the nature, structure, and course of adolescent alcohol problems is necessary for meaningful research progress on the etiology and treatment of these problems. However, current nosological systems for alcohol use disorders have largely developed from research and clinical experience with adults. The primary goal of this research is to contrast the validity of different taxonomic systems for alcohol use disorders when applied to adolescents. This project will utilize all subjects who participate in PAARC'S Clinical Core assessment. The sample will contain a large number of male and female adolescents. Half of each gender will have a DSM-IV diagnosis of Alcohol Abuse or Dependence. Subjects without an alcohol diagnosis will provide a broad range of drinking and alcohol-related problems. Symptoms, diagnoses, independent problem measures, and alcohol and drug use will be assessed at baseline and several longitudinal follow ups. These design features provide standardized assessment of problems across a range of severity, with a developmental emphasis on staging and course. Measures include the Structured Clinical Interview for the DSM (SCID), independent measures of alcohol dependence and psychosocial dysfunction, and alcohol and drug use data. The SCID has been adapted to assess DSM-IV and ICD-10 symptoms, and other problem domains relevant to adolescents, providing a comprehensive assessment of alcohol symptomatology in this population. The reliability, covariation, diagnostic efficiency, and severity weighting of symptoms will be determined. We will examine which diagnostic criteria are most appropriate for adolescents. The staging and course over time of alcohol symptoms and disorders will be determined. Preliminary data suggest a new formulation of adolescent alcohol abuse, defined by heavy and dyscontrolled drinking with associated social and interpersonal problems. The concurrent and predictive validity of this definition will be contrasted with DSM-IV Alcohol Abuse and ICD-10 Harmful Use diagnoses. Other analyses will contrast the concurrent and predictive validity of different definitions of alcohol dependence. This research will yield important information on the development and nature of adolescent alcohol problems.

了解青少年酒精的性质，结构和过程 问题对于病因的有意义的研究进展是必要的 处理这些问题。 但是，当前用于 酒精使用障碍主要是由研究和临床发展的 成人的经验。 这项研究的主要目标是对比 不同的分类系统对酒精使用障碍的有效性 应用于青少年。 该项目将利用参加PAARC临床的所有主题 核心评估。 样本将包含大量男性和女性 青少年。 每种性别的一半将对酒精进行DSM-IV诊断 滥用或依赖。 没有酒精诊断的受试者将提供 广泛的饮酒和与酒精有关的问题。 症状， 诊断，独立的问题措施以及酒精和吸毒将是 在基线和几个纵向随访中进行评估。 这些设计 功能提供了对一系列问题的标准化评估 严重性，发育强调分期和课程。 措施 包括DSM（SCID）的结构化临床访谈，独立 酒精依赖和社会心理功能障碍和酒精的度量 和药物使用数据。 SCID已适应评估DSM-IV和ICD-10 症状以及与青少年有关的其他问题领域，提供了 对该人群中酒精症状的全面评估。 这 可靠性，协方差，诊断效率和严重性加权 将确定症状。 我们将检查哪些诊断标准是 最适合青少年。 随着时间的推移的舞台和课程 将确定酒精症状和疾病。 初步数据 建议对青少年酗酒的新表述，该滥用由重量和 与相关的社交和人际交往问题的饮酒失调。 该定义的并发和预测有效性将是 与DSM-IV酒精滥用和ICD-10有害使用诊断形成对比。 其他分析将对比 酒精依赖的不同定义。 这项研究将产生 有关青少年酒精的发展和性质的重要信息 问题。