CORE--MORPHOLOGY/IMAGING FACILITY

核心——形态学/成像设备

• 批准号: 6105478
• 负责人: ROBERT D SPECIAN
• 金额: $ 13.6万
• 依托单位: LOUISIANA STATE UNIV HSC SHREVEPORT
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-01 至 1999-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6105478
• 关键词: biomedical facility; confocal scanning microscopy; electron microscopy; histology; light microscopy; morphology; tissue /cell culture; tissue /cell preparation

In order to provide core support for the research projects, the Program Project Grant has four Core units, i.e., an Administrative Core (P.I.; D.N.Granger), a Cell Culture Core (P.I.; P.R Kvietys), a Biochemistry Core (P/I/; M.B. Grisham), and a Morphology Core (P.I.; R. Specian). These Cores will provide shared facilities and resources for the investigators in the PPG and play an important role in enhancing the interaction among investigators. The primary functions of the Administrative Core are to co- ordinate the activities of the component Projects and Cores, to manage purchasing and budgetary matters, to provide secretarial support for the various Projects and Cores, and to schedule meetings and seminars in the PPG. The cell Culture Core will provide cultured endothelial and epithelial cells for specific Projects in the PPG. The Biochemistry Core will perform various spectrophotometric and fluorometric assays, protein separation and purification, and enzyme inactivation procedures for several projects. The Morphology Core will provide facilities and expertise for light and electron microscopic studies of the mucosal membrane, blood vessels, leukocytes, and cultured endothelial cells. The four Core units will provide an efficient means for generating the services needed to conduct the proposed research and to attain the stated goals of the Program.

为了为研究项目提供核心支持，该计划 Project Grant有四个核心单位，即行政核心（P.I。； D.N. Granger），一种细胞培养核心（P.I。; P.R Kvietys），生物化学核心 （P/I/; M.B. Grisham）和形态核心（P.I。; R. Specian）。 这些 核心将为调查人员提供共享的设施和资源 PPG并在增强相互作用方面发挥重要作用 调查人员。 行政核心的主要功能是共同 辅助组件项目和核心的活动，以管理 采购和预算事项，为 各种项目和核心，并安排会议和研讨会 ppg。 细胞培养核心将提供培养的内皮和 PPG中特定项目的上皮细胞。 生物化学核心 将执行各种分光光度法和荧光测定法，蛋白质 分离和纯化，以及酶的灭活程序 项目。 形态核心将为设施和专业知识提供 粘膜膜的光和电子显微镜研究 血管，白细胞和培养的内皮细胞。 四个核心单元 将提供一种有效的手段来生成所需的服务 进行拟议的研究并实现既定目标 程序。