Application for Strategic Priorities Fund: Clean Air Champion

战略优先基金申请：清洁空气冠军

• 批准号: NE/T002069/1
• 负责人: Stephen Holgate
• 金额: $ 67.61万
• 依托单位: University of Southampton
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2019
• 资助国家: 英国
• 起止时间: 2019 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=NE%2FT002069%2F1
• 关键词: Application; Strategic; Priorities; Fund; Clean

Air pollution has long been known to damage health and the environment, with recent research adding considerably to the knowledge base on how this occurs and why. However air pollution can be thought of as a wicked problem where no single solution will create the desired reductions necessary to meet targets based on health set by the WHO. The Clean Air Champion(s) roles are to drive forward new research into air pollution in relation to adverse health and effects on the wider environment environment. At present we know that air pollution of all types and from multiple sources causes damage to living cells whether human, animals or plants. However, understanding the total exposure to air pollutants and mixtures across 24 hours and over much longer periods in real world settings is largely unknown. The advent of new technologies in the field for personal and more localised pollution monitoring coupled with improved markers of damage and worsening of diseases will greatly strengthen the information required to introduce control of emissions and mitigation strategies for the benefit of society. Technologies that can be sustaining or disruptive also have a key role in cleaning up the air around us. The ability to create predictive models of adverse air pollution outcomes in relation to climate conditions, urban settings and indoors is an important part of this Air Pollution Solutions programme, but any such model requires validation with real world observations. There is an urgent need to break down traditional barriers between physical, biological and health scientists on the one hand and the research community, industry and local and central government to translate knew knowledge on pollution to benefit the health and wealth of society.To achieve these aims, this proposal for a Clean Air Champion(s) lays out a strategy and a delivery plan to strengthen the field and through interdisciplinary working create more joined up working that will translate into benefits to the public at large and create new opportunities for industry as this and other countries get closer to replacing pollution emitting sources by cleaner technologies. A further role for the Champion(s) is to promote greater public awareness and understanding of the adverse effect of air pollution and to offer ways forward where everyone can play their role in driving down pollution levels. The aims of the Clean Air Champion(s)will be: 1) Identify and then undertake a mapping exercise to discern the goals and problems to be solved. T; 2) Unify key researchers and stakeholders around visionary missions using a range of tools to engage the different communities ranging; 3) Uncover and challenge barriers/obstacles and produce workable interdisciplinary solutions; 4) Create new ideas leading to new interventions to test; 5) Translate these ideas into practical activities targeted at the right audiences; 6) Develop a professional and public communications strategy using the best available evidence available and convert these into positive messaging. We see a particular role for early career researchers throughout the whole programme since they will become the leaders who will ensure novel and ambitious goals are set and that the programme becomes sustainable.People will change their behaviour only if they see the new behaviour as easy, rewarding, empowering and normal. Although the work will be coordinated from Southampton and Kings College, London, the activity has to be national in character and sufficiently ambitious to drive change.

长期以来，众所周知，空气污染会损害健康和环境，最近的研究大大增加了有关这种情况的发生以及原因的知识基础。但是，可以将空气污染视为一个邪恶的问题，在该问题中，没有一个解决方案会根据世卫组织设定的健康而产生所需的减少目标。清洁空气冠军的角色是推动与不利健康和对更广泛环境的影响有关的空气污染的新研究。目前，我们知道所有类型的空气污染和多种来源都会损害人类，动物或植物。但是，在24小时内，在现实世界中，了解整个空气污染物和混合物的总暴露在很大程度上是未知的。该领域中新技术的出现，以进行个人和更本地化的污染监测，加上改善的损害标记和疾病恶化的标志，将大大加强引入对排放和缓解策略的控制所需的信息，以使社会受益。可以维持或破坏性的技术在清理我们周围的空气方面也具有关键作用。与气候条件，城市环境和室内相关的不利空气污染结果的预测模型的能力是该空气污染解决方案计划的重要组成部分，但是任何此类模型都需要对现实世界观察进行验证。一方面，迫切需要打破物理，生物学和健康科学家之间的传统障碍，而研究社区，行业，地方和中央政府则可以翻译有关污染的知识知识，以使社会的健康和财富受益。实现这些目标，这项对清洁空气冠军的建议（S）提出了一项清洁空气冠军的提议，以提高策略，并通过跨学科的工作来提高策略，从而使企业融为一体，从而使企业的努力构成了跨学科的工作，从而使企业融入了企业，从而使自己的努力构成了跨学科的工作，从而构成了跨学科的努力，以实现跨学科的工作，以实现跨学科的工作，以实现跨学科的工作，以实现跨学科的工作，以实现跨学科的努力，以实现跨学科的工作。其他国家越来越接近替换清洁技术发出的污染来源。冠军的另一个作用是提高公众对空气污染的不利影响的认识和理解，并提供前进的方向，每个人都可以在降低污染水平方面发挥作用。清洁空气冠军的目的是：1）识别然后进行映射练习，以辨别要解决的目标和问题。 t; 2）使用一系列工具与不同社区的不同工具统一关键的研究人员和利益相关者； 3）发现和挑战障碍/障碍，并产生可行的跨学科解决方案； 4）创建新的想法，导致新的干预措施进行测试； 5）将这些想法转化为针对合适受众的实用活动； 6）使用可用的最佳证据制定专业和公共通信策略，并将其转换为积极的消息传递。我们在整个计划中看到了早期职业研究人员的特殊角色，因为他们将成为领导者，他们将确保设定新颖而雄心勃勃的目标，并且该计划变得可持续。人们只有在他们认为新行为是简单，有意义，授权，授权和正常状态的情况下，他们才会改变其行为。尽管这项工作将从伦敦的南安普敦和国王学院进行协调，但该活动必须具有全国性，并且足够雄心勃勃才能推动变革。

项目成果

Air pollution: The time has arrived for the medical profession to take ownership of the problem and act

• DOI: 10.1111/resp.13690
• 发表时间: 2019-09
• 期刊: Respirology
• 影响因子: 6.9
• 作者: S. Holgate

Is exposure to pollen a risk factor for moderate and severe asthma exacerbations?

• DOI: 10.1111/all.15724
• 发表时间: 2023-04-10
• 期刊: ALLERGY
• 影响因子: 12.4
• 作者: Annesi-Maesano，Isabella;Cecchi，Lorenzo;Agache，Ioana
• 通讯作者: Agache，Ioana

The impact of indoor pollution on asthma-related outcomes: A systematic review for the EAACI guidelines on environmental science for allergic diseases and asthma

• DOI: 10.1111/all.16051
• 发表时间: 2024-02-17
• 期刊: ALLERGY
• 影响因子: 12.4
• 作者: Agache，Ioana;Canelo-Aybar，Carlos;Akdis，Cezmi A.
• 通讯作者: Akdis，Cezmi A.

Letter from the UK (if we still exist after recent events!): Air pollution: The public health challenge of our time.

来自英国的信（如果我们在最近的事件之后仍然存在！）：空气污染：我们这个时代的公共卫生挑战。

• DOI: 10.1111/resp.13475
• 发表时间: 2019
• 期刊: Respirology (Carlton, Vic.)
• 作者: Holgate ST