COURSE OF TREATMENT RESISTANT DEPRESSION

难治性抑郁症的病程

• 批准号: 6297858
• 负责人: ANDREW A NIERENBERG
• 金额: $ 0.06万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6297858
• 关键词: MAO inhibitors; antidepressants; clinical research; clinical trial phase I; combination chemotherapy; drug screening /evaluation; human subject; human therapy evaluation; lithium; major depression; mental disorder chemotherapy; nortriptyline

This study will access sequential treatments for patients with treatment-resistant depression: first, a trial of nortriptyline; second, the antidepressant efficacy of the addition of lithium to the failed trial of nortiptyline; third, tranylcypromine with or without lithium for those patients who do not respond to lithium augmentation of nortriptyline.

这项研究将为患有以下疾病的患者提供序贯治疗 难治性抑郁症：首先尝试去甲替林； 第二，添加锂的抗抑郁功效 去甲替林试验失败；第三，反苯环丙明有或没有 锂盐适用于那些对锂盐增强治疗无反应的患者 去甲替林。