CHILDRENS CANCER GROUP--COMPETITIVE GRANT RENEWAL

儿童癌症组——竞争性拨款更新

• 批准号: 6124650
• 负责人: DAVID L BAKER
• 金额: $ 6.84万
• 依托单位: PRINCESS MARGARET HOSPITAL FOR CHILDREN
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-01-20 至 2003-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6124650
• 关键词: acute lymphocytic leukemia; acute myelogenous leukemia; antineoplastics; bone marrow transplantation; bone neoplasms; brain neoplasms; clinical research; clinical trials; combination cancer therapy; combination chemotherapy; cooperative study; cytogenetics; data management; human subject; human therapy evaluation; liver neoplasms; lymphoma; molecular oncology; neoplasm /cancer chemotherapy; neoplasm /cancer diagnosis; neoplasm /cancer epidemiology; neoplasm /cancer immunotherapy; neoplasm /cancer pharmacology; neoplasm /cancer radiation therapy; neoplasm /cancer surgery; neuroblastoma; oncology nursing; pediatric neoplasm /cancer; statistics /biometry; tissue resource /registry

Princess Margaret Hospital for Children (PMH) is the sole tertiary university affiliated paediatric teaching hospital for the State of Western Australia and provides the only multidisciplinary paediatric oncology service in the state, which has a population of 2 million. PMH is the only hospital outside North America honoured by being accepted as a CCG member (elected November 1990). Promotion from probationary to full membership was achieved in November 1992. In the last 12 months PMH has entered 70 patients on CCG therapeutic, biologic and non- therapeutic studies. With respect to the overall institutional ranking for 1997 based on a standardised CCG ranking system, PMH achieved a ranking of 19 (compared with 26 in 1996), the best incremental improvement of all CCG affiliated hospitals. The Oncology Division is housed in a purpose built "Total Care Unit" containing all services and disciplines in the one locality needed to manage children with cancer their families and includes inpatient, haemopoietic stem cell transplant, same day care, outpatient, treatment rooms, pharmacy, data management, social work, school room and nurse liaison facilities. The Oncology Division goals are four-fold: (1) Provide state of the art multidisciplinary management which will maximise probabilities of cure for oncological diseases in children. (2) Tailor curative therapy to minimise both acute toxicity and long term deleterious sequelae. (3) Support scientifically sound clinical research through the application of IRB approved co- operative group clinical trials. (4) Promote translational research through active support of CCG approved biologic studies. These aims are best achieved by PMH's commitment to fulfilling all the requirements and responsibilities necessary in maintaining full membership with the Children's Cancer Group. The long term objective of the Oncology Division at PMH is to play a more pro-active role in CCG activities including steering and study committees and strategy group membership.

玛格丽特公主儿童医院（PMH）是西澳大利亚州唯一的三级大学附属儿科教学医院，并提供该州唯一的多学科儿科肿瘤科服务，该服务人口为200万。 PMH是北美以外的唯一一家因被录取为CCG成员而受到尊敬的医院（1990年11月当选）。 1992年11月，从试验到正式成员的晋升。在过去的12个月中，PMH进入了70名CCG治疗，生物学和非治疗研究的患者。 关于基于标准化CCG排名系统的1997年整体机构排名，PMH的排名为19（比1996年为26），这是所有CCG附属医院的最佳增量改善。 肿瘤学部门以目的建立的“全面护理单位”为内部，其中包含所有服务和学科，以管理患有癌症的儿童家人所需的一个地区，其中包括住院，阳性型干细胞移植，同期，门诊，治疗室，药房，药房，药房，数据管理，社交工作，社交工作，学校房间和养育机构。肿瘤学部门的目标是四倍：（1）提供最先进的多学科管理状态，这将最大程度地提高儿童肿瘤学疾病的概率。 （2）调整治疗疗法以最大程度地减少急性毒性和长期有害后遗症。 （3）通过应用IRB认可的合作组临床试验的应用来支持科学的临床研究。 （4）通过积极支持CCG认可的生物学研究来促进转化研究。 PMH致力于履行与​​儿童癌症组完全成员所必需的所有要求和责任的承诺，最好实现这些目标。 PMH肿瘤学部门的长期目标是在CCG活动中发挥更积极的作用，包括转向和研究委员会和战略小组成员资格。