UC Davis AP4 Center

加州大学戴维斯分校 AP4 中心

• 批准号: 6830951
• 负责人: KIT S LAM
• 金额: $ 7.43万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-07-01 至 2005-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6830951
• 关键词: acute lymphocytic leukemia; antineoplastics; bioimaging /biomedical imaging; cooperative study; drug design /synthesis /production; drug discovery /isolation; imaging /visualization /scanning; myelogenous leukemia; neoplasm /cancer; neoplasm /cancer chemotherapy; neoplasm /cancer diagnosis; neoplasm /cancer pharmacology; orphan disease /drug; ovary neoplasms; sarcoma; technology /technique development

DESCRIPTION (provided by applicant): In July 2002, UC Davis Cancer Center successfully obtaining NCI center designation. Cancer Therapeutics is one of six major programs in the Cancer Center Support Grant and that program will provide the leadership and direction for the proposed AP4 Center. The Therapeutics Program is led by co-directors Kit S. Lam MD, PhD and David Gandara MD and consists of 50 investigators who work collaboratively on three main themes: 1) Drug Discovery, 2) Drug Development and 3) Clinical Investigations and Correlative Studies. Dr. Lam, who has a strong background in developing multidisciplinary research teams and public/private partnerships, will serve as the AP4 Center principal investigator. The proposed AP4 Center will focus on developing new therapeutics and technologies for the treatment, diagnosis and imaging of a range of orphan cancers such as acute myelocytic leukemia, acute lymphocytic leukemia and ovarian cancer. The specific aims of the planning grant are to: 1. Hold a 1-2 day planning meeting with a group of potential Center researchers, corporate partners, non-profit organizations and state agencies 2. Engage in a strategic planning process that develops the proposed AP4 Center's vision and mission statements and research agenda 3. Select at least three primary and two alternate research projects that focus on orphan cancers to include in the AP4 Center application 4. Negotiate a membership agreement with corporate, non-profit and government partners that serves as a formal operations document and specifies the proposed Center's structure and policies 5. Prepare an AP4 Center application for submission to NCI in 2005

描述（由申请人提供）： 2002年7月，加州大学戴维斯分校癌症中心成功获得了NCI中心的名称。癌症治疗学是癌症中心支持补助金的六个主要计划之一，该计划将为拟议的AP4中心提供领导和指导。 Therapeutics计划由联合导演Kit S. Lam MD，PhD和David Gandara MD领导，由50名研究人员组成，他们在三个主要主题上合作：1）药物发现，2）药物开发和3）临床研究和相关研究。 Lam博士在发展多学科研究团队和公共/私人合作伙伴关系方面具有良好的背景，他将担任AP4中心首席研究员。 拟议的AP4中心将着重于开发新的治疗疗法和技术，用于治疗，诊断和成像一系列孤儿癌，例如急性骨髓细胞性白血病，急性淋巴细胞性白血病和卵巢癌。规划赠款的具体目的是： 1。与一组潜在的中心研究人员，公司合作伙伴，非营利组织和州机构举行1日的计划会议 2.参与战略规划过程，该过程开发了拟议的AP4中心的愿景和任务陈述和研究议程 3。选择至少三个主要和两个替代研究项目，这些项目专注于孤儿癌，以包括在AP4中心申请中 4。与公司，非营利组织和政府合作伙伴协商一项会员协议，该协议是正式运营文件，并指定了拟议中心的结构和政策 5。准备AP4中心申请，以便于2005年提交给NCI