CLINICAL TRIALS NETWORK MID-ATLANTIC COLLABORATIVE GROUP

临床试验网络中大西洋合作小组

• 批准号: 6174876
• 负责人: ROBERT K BROONER
• 金额: $ 220万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-30 至 2004-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6174876
• 关键词: behavior therapy; behavioral /social science research tag; buprenorphine; clinical research; clinical trials; cocaine; community mental health services; cooperative study; drug abuse chemotherapy; drug abuse therapy; health services research tag; human subject; human therapy evaluation; methadone; training

This is a proposal to create a Mid-Atlantic regional node of the planned NIDA National Drug Abuse Treatment Clinical Trials Network. This Mid-Atlantic region incorporates Maryland, Virginia, and Washington, D.C., and involves a collaborative effort among major universities in the region (Johns Hopkins University School of Medicine, Virginia Commonwealth University, University of Maryland) and a diverse array of community drug abuse treatment programs. These community treatment programs provide clinical research access to a large population of drug abuse patients with great demographic, diagnostic, and syndromal diversity, as well as to treatment programs representing great diversity in the types, modalities, and focus of their treatment service delivery. These academic and community treatment programs have established strong collaborative relations and are jointly committed to systematic community-based research that will assess the effectiveness of different drug abuse treatments and services directly in community treatment programs, and that will assess and study factors related to adoption of improved treatments, as requested in the RFA. The academic centers have extensive experience and expertise in conducting and managing controlled clinical trials of drug abuse treatments, including both behavioral treatments and pharmacological treatments, as well as integrated behavioral-pharmacological treatments, for a broad range of different types of substance use disorders (heroin, cocaine, sedatives, alcohol, tobacco). The centers also have extenisve experience and expertise in training, implementation, and assessment within community treatment programs. This collaborative group proposes to participate in the NIDA Clinical Trials Network, to conduct controlled trials of behavioral and/or pharmacological drug abuse treatments in community clinics, and to investigate the process of and influences on community clinic adoption of new treatments.

这是一项提议，旨在创建计划中的NIDA国家药物滥用治疗临床试验网络的中大西洋区域节点。 这个大西洋中部地区融合了马里兰州，弗吉尼亚州和华盛顿特区，并涉及该地区主要大学（约翰·霍普金斯大学，马里兰大学约翰·霍普金斯大学医学院，马里兰州的约翰·霍普金斯大学医学院）和各种社区药物滥用治疗计划。 这些社区治疗计划为人口，诊断和综合症多样性的大量吸毒患者提供了临床研究，以及代表其治疗服务提供类型，方式和重点的治疗计划。 这些学术和社区治疗计划已经建立了牢固的合作关系，并共同致力于系统的基于社区的研究，该研究将直接评估不同药物滥用治疗和服务在社区治疗计划中的有效性，并将根据RFA的要求评估和研究与采用改进治疗的相关因素。 这些学术中心在进行和管理药物滥用治疗的对照临床试验方面具有丰富的经验和专业知识，包括行为治疗和药理学治疗，以及综合行为 - 药理学治疗，用于多种不同类型的药物使用障碍（海洛因，可卡因，可卡因，塞药，sediatent，sedinates，sedinates，chockhabol，tobacco）。 这些中心还具有社区治疗计划中的培训，实施和评估方面的分散经验和专业知识。 这个合作小组建议参加NIDA临床试验网络，在社区诊所进行行为和/或药理药物滥用治疗的对照试验，并研究对社区诊所采用新治疗的过程和影响。