COLD SPRING HARBOR LAB CONFERENCE ON GAMETOGENESIS

冷泉港配子发生实验室会议

• 批准号: 6158880
• 负责人: TERRI I. GRODZICKER
• 金额: $ 0.6万
• 依托单位: COLD SPRING HARBOR LABORATORY
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-01 至 2001-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6158880
• 关键词: fertilization; gametogenesis; germ cells; meeting /conference /symposium; travel

Germ cells are set aside from other lineages early in development, and differentiate into functioning gametes. To understand germ cell differentiation would be a major achievement in biology, and would provide important insights into infertility, contraception, human congenital diseases, germ line tumors, as well as the preservation of endangered species. The molecular basis of germ cell differentiation is beginning to be understood, due to major intellectual and technical advances. General mechanisms that unite both vertebrates and invertebrates are beginning to emerge. This meeting will provide a public forum for discussion of all aspects of germ cell research, from the primordial germ cell to the functioning gamete, in diverse model organisms. We expect to attract 200-250 participants from all over the world. There are no competing meetings that are so wide in scope. Six topics have been chosen for platform presentations: The early germ line, Regulation of germ cell gene expression, Meiosis, Sperm differentiation, Oogenesis and egg polarity, Fertilization and gamete function. Each will be organized and co-chaired by two experts in the topic, who will invite half the speakers, and select the other half from submitted abstracts. We will encourage platform presentations from young scientists. The meeting will facilitate interactions between scientists who study different model systems, and different aspects of germ cell differentiation.

生殖细胞在开发的早期远离其他谱系，并分化为功能性配子。 了解生殖细胞的分化将是生物学的一项重大成就，并将为不育，避孕，人类先天性疾病，生殖系肿瘤以及濒危物种的保存提供重要的见解。 由于主要的智力和技术进步，生殖细胞分化的分子基础开始被理解。统一脊椎动物和无脊椎动物的一般机制已开始出现。这次会议将提供一个公共论坛，讨论从原始生殖细胞到功能性的生物体中的生殖细胞研究的各个方面。 我们希望吸引来自世界各地的200-250名参与者。 没有竞争会议的范围如此之大。为平台演示选择了六个主题：早期生殖线，生殖细胞基因表达的调节，减数分裂，精子分化，卵子发生和卵极性，受精和配子功能。 每个主题的两位专家将组织和共同主持，他们将邀请一半的扬声器，并从提交的摘要中选择另一半。 我们将鼓励年轻科学家的平台演讲。 这次会议将促进研究不同模型系统的科学家与生殖细胞分化的不同方面之间的相互作用。