RELAPSE ONSET AND TERMINATION AND ABSTINENCE MAINTENANCE

复发发作和终止以及戒断维持

• 批准号: 6421074
• 负责人: WILLIAM H ZYWIAK
• 金额: $ 13.27万
• 依托单位: PACIFIC INSTITUTE FOR RES AND EVALUATION
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-03 至 2002-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6421074
• 关键词: alcoholic beverage consumption; alcoholism /alcohol abuse information system; alcoholism /alcohol abuse therapy; behavioral /social science research tag; clinical research; clinical trials; disease /disorder onset; gender difference; human data; outcomes research; perception; prognosis; psychometrics; questionnaires; racial /ethnic difference; relapse /recurrence; substance abuse epidemiology

The overarching goal of this study is to advance understanding of alcohol treatment outcome. This study will focus on four aspects of treatment outcome: 1) client perceived influences of relapse onset 2) client perceived influences of relapse termination 3) client perceived influences of periods of abstinence, and 4) temporal and alcohol-related parameters of relapse. Whereas relapse onset has received considerable attention in alcohol research, relapse termination and abstinence maintenance have received less attention. Since a data set is readily available (the Project MATCH data base; N = 1726) to do this, the cost of this study will be reduced considerably. The Relapse Questionnaire was administered in Project MATCH at the posttreatment, 6, and 12-month follow-ups. This Questionnaire consists of three sectiOns, which multidimensionally assess characteristics of relapse onset, relapse termination, and abstinence maintenance. The aims of the study are 1) to empirically determine the underlying structure of each section of this questionnaire, 2) to determine the interrelationships of temporal and alcohol-related parameters of relapse, 3) to determine the interrelationships of relapse onset, relapse termination and abstinence maintenance characteristics and the relationships of these three domains to temporal and alcohol- related parameters of relapse and general treatment outcome, 4) to determine the consistency of relapse onset, relapse termination, and abstinence maintenance over time, and to examine how consistency and changes in relapse onset and abstinence maintenance are related to treatment outcome, and 5) to examine the generalizability of the Relapse Questionnaire scales across Clinical Research Units, treatments, gender, and ethnicity. These analyses will have many implications regarding ways in which alcohol treatment can become more effective. For instance, the most dangerous relapse onset characteristics will be identified, the most efficacious abstinence maintenance methods will be identified, and the prognostic value of pretreatment relapse termination characteristics will be ascertained.

这项研究的总体目标是提高对酒精治疗结果的了解。这项研究将重点关注治疗结果的四个方面：1）客户感知的复发性发作的影响2）客户感知的复发终止的影响3）客户感知的禁欲时期的影响，而4）4）与暂时的和酒精相关的复发参数。虽然复发发作在酒精研究中受到了很大的关注，但复发终止和戒酒维持的关注较少。由于很容易获得数据集（项目匹配数据库； n = 1726），因此该研究的成本将大大降低。复发问卷是在治疗后的6个和12个月的随访中在项目比赛中管理的。该问卷由三个部分组成，这些部分在多维上评估复发发作，复发终止和节制维持的特征。研究的目的是1）在经验上确定该问卷每个部分的基础结构，2）确定复发的时间和酒精相关参数的相互关系，3）确定复发开始，复发终止和戒断范围和相关范围的相关性和酒精相关参数的相互关联的相互关系，以确定相关的次数，并确定相关的相关参数相关参数，该范围与酒精相关的参数相关的关系相关的关系，随着时间的流逝，复发性发作，复发终止和禁欲维持，并研究复发性发作和禁欲维持的一致性和变化与治疗结果以及5）相关，以检查复发性调查表范围跨临床研究单位，治疗，性别，性别和种族的概括性的普遍性。这些分析将对酒精治疗变得更有效的方式有许多影响。例如，将确定最危险的复发发作特征，将确定最有效的节制维持方法，并将确定预处理复发终止特征的预后价值。

项目成果

Alcohol relapse repetition, gender, and predictive validity.

酒精复发重复、性别和预测有效性。

• DOI: 10.1016/j.jsat.2006.03.004
• 发表时间: 2006
• 期刊: Journal of substance abuse treatment.
• 作者: Zywiak,WilliamH;Stout,RobertL;Trefry,WinstonB;Glasser,Irene;Connors,GerardJ;Maisto,StephenA;Westerberg,VernerS
• 通讯作者: Westerberg,VernerS

Exploratory findings from the Reasons for Drinking Questionnaire.

• DOI: 10.1016/s0740-5472(03)00118-1
• 发表时间: 2003-12
• 期刊: Journal of substance abuse treatment
• 影响因子: 3.9
• 作者: W. Zywiak;V. Westerberg;G. Connors;S. Maisto