SYNTHESIS OF SELECTED CHEMICAL CARCINOGENS

选定化学致癌物的合成

• 批准号: 6044594
• 负责人: PAUL H RUEHLE
• 金额: $ 31.61万
• 依托单位: CHEMSYN SCIENCE LABORATORIES
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-09-30 至 2002-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6044594
• 关键词: carbopolycyclic compound; chemical carcinogen; chemical registry /resource; chemical synthesis; method development

The objectives of this contract are:(1) Resynthesis of polycyclic aromatic hydrocarbon PAH derivatives by established procedures for the restocking of NCI's Chemical Carcinogen Reference standards Repository as necessary; and (2) Development of synthesis or purification procedures for the preparation of a wide spectrum selected chemical carcinogens, chemopreventive agents and certain their metabolites or derivatives.

该合同的目标是：（1）多环的重新合成 芳香烃PAH衍生物通过既定的程序 NCI化学​​致癌参考标准存储库的补货 必要； （2）综合或纯化的发展 制备广泛选择化学的程序 致癌物，化学预防剂及其代谢产物或 衍生物。