CHARACTERIZATION OF CORNEALED CELL SURFACE ANTIGENS: WOUND HEALING

角膜细胞表面抗原的表征：伤口愈合

• 批准号: 6295106
• 负责人: NIRMALA SUNDARRAJ
• 金额: $ 1.17万
• 依托单位: MELLON PITTS CORPORATION (MPC CORP)
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-30 至 1999-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6295106
• 关键词: Mammalia; animal tissue; bacteria; biological products; biomedical resource; biotechnology; connective tissue; enzymes; eye; growth /development; human tissue; proteins

Several unique cytoskeletal and extracellular matrix proteins associated with corneal wound healing have been identified. cDNA clones containing sequences complementary to mRNAs of some of these proteins have been determined. Partial amino acid sequences of their DNAs is underway. These data will be used to determine whether the proteins under investigation have sequences that match any of the reported sequences using sequence databases available at the Pittsburgh Supercomputing Center. The software packages available at the center will also be used for characterizing special features of the structure of these proteins.

几种独特的细胞骨架和细胞外基质蛋白 已确定与角膜伤口愈合有关。 cDNA 含有与其中一些的 mRNA 互补的序列的克隆 蛋白质已测定。 其部分氨基酸序列 DNA 正在进行中。 这些数据将用于确定是否 正在研究的蛋白质具有与任何以下序列相匹配的序列 使用序列数据库报告序列 匹兹堡超级计算中心。 软件包位于 该中心还将用于表征 这些蛋白质的结构。