INSULIN IN FSH INDUCED OVARIAN RESPONSE IN PCOS

FSH 中的胰岛素引起 PCOS 患者的卵巢反应

• 批准号: 6265199
• 负责人: JEFFREY T CHANG
• 金额: $ 1.15万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6265199
• 关键词: clinical research; drug interactions; drug screening /evaluation; female; follicle stimulating hormone; hormone regulation /control mechanism; human subject; human therapy evaluation; insulin; insulin sensitivity /resistance; polycystic ovary syndrome; reproductive system disorder chemotherapy

Determine the role of insulin on FSH-induced ovarian responses in polycystic ovary syndrome (PCOS) and in normal women. The hypothesis is that in normal women early ovarian responsiveness to FSH is enhanced by insulin whereas in PCOS ovarian responses are resistant to this synergistic action of insulin.

确定胰岛素对多囊卵巢综合征 (PCOS) 和正常女性 FSH 诱导的卵巢反应的作用。 假设是，在正常女性中，胰岛素可以增强卵巢对 FSH 的早期反应，而在 PCOS 中，卵巢反应对胰岛素的这种协同作用具有抵抗力。