PERUVIAN MEDICAL PLANTS & SOURCES OF NEW PHARMACEUTICALS

秘鲁药用植物

• 批准号: 6118554
• 负责人: WALTER H LEWIS
• 金额: $ 0.05万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-08-01 至 1999-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6118554
• 关键词: biological products; biomedical resource; spectrometry

Long-term objectives are to provide the materials whereby biodynamic compounds will be discovered and developed as pharmaceuticals for improving human well-being in specific health areas, while at the same time providing for sustained economic growth and the conservation of biodiversity in northern Peru. Fundamental to those aims is the collection and screening of plants that have been used medicinally by peoples in Peru and elsewhere in South America for generations to treat broad ranges of illnesses. Primary screens will be conducted to test for activity against a number of infectious agents, including respiratory viruses, herpes viruses, pathogenic yeasts, and tuberculosis. When crude extracts prove positive biodirected assays will allow active fractions to be identified. Isolation and characterization of these principles will provide phytochemicals that could be developed into new pharmaceuticals. Mass spectrometry is used in their characterization.

长期目标是提供材料 生物动力化合物将被发现并开发为 用于改善特定健康中人类福祉的药品 区域，同时为持续的经济增长提供 以及秘鲁北部生物多样性的保护。 对 这些目的是收集和筛查已经 秘鲁和南美其他地方的人民用药物使用 几代人治疗广泛的疾病范围。 主屏幕将 进行测试以测试许多感染性的活动 药物，包括呼吸病毒，疱疹病毒，致病性 酵母和结核病。 当原油提取被证明是阳性时 生物形式的测定将允许识别主动分数。 这些原则的隔离和表征将提供 可以发展为新药物的植物化学物质。 大量的 光谱法用于其表征。