CORE--SPECTROMETER CONSTRUCTION AND UPGRADES, AND DNA SYNTHESIS

核心——光谱仪构建和升级，以及 DNA 合成

• 批准号: 6107519
• 负责人: BRIAN R REID
• 金额: --
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-01-01 至 1998-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6107519
• 关键词: DNA; biomedical equipment development; biomedical facility; magnetic field; nuclear magnetic resonance spectroscopy; nucleic acid chemical synthesis; nucleic acid sequence; phosphorus compounds; physical separation; stable isotope; superconductivity; DNA; biomedical equipment development; biomedical facility; magnetic field; nuclear magnetic resonance spectroscopy; nucleic acid chemical synthesis; nucleic acid sequence; phosphorus compounds; physical separation; stable isotope; superconductivity

The Core Laboratory goals for the next five-year grant period will be to; 1). Design to construct a new multi-channel NMR spectrometer operating at a 1H frequency of 750 MHZ. 2). Upgrade and maintain the two current 500 MHz spectrometers constructed with program project funds and owned by the program project. 3). Synthesize and purify routine DNA samples of varying g sequence for the participating laboratories in the program project. 4). Synthesize and purify DNA samples containing atom-specific and site- specific isotopic labels for members of the program project. The Core laboratory will continue to be a service facility to the entire six-lab Program Project.

接下来的五年赠款期的核心实验室目标将是； 1）。设计以构建新的多通道NMR光谱仪操作 以750 MHz的1小时频率。 2）。 升级并维护两个当前的500 MHz光谱仪 由计划项目资金构建，并由计划项目拥有。 3）。合成和纯化不同G序列的常规DNA样品的常规DNA样品 计划项目的参与实验室。 4）。合成和纯化含有原子特异性和位点的DNA样品 该计划项目成员的特定同位素标签。 核心实验室将继续成为整个整个的服务机构 六车计划项目。