KU Nanofabrication Facility

KU 纳米制造设施

基本信息

批准号：
10654655
负责人：
Susan M Lunte
金额：
$ 22.95万
依托单位：
UNIVERSITY OF KANSAS LAWRENCE
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-07-01 至 2027-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10654655
关键词：
Biological Biological Process Biology Biomedical Research Biophysics Cancer Patient Cell Communication Cells Centers of Research Excellence Chemicals Chemistry Clinical Clinical Chemistry Complex Custom DNA Sequencing Facility Development Devices Disease Pathway Electronics Engineering Environment Equipment Goals Growth Hematopoietic Neoplasms Human Human Resources Infrastructure Institution Investigation Kansas Lab On A Chip Laboratories Methods Microfabrication Microfluidic Microchips Microfluidics Molecular Analysis Neoplasm Circulating Cells Organ Phase Physics Physiological Processes Privatization Process Production Research Research Infrastructure Research Personnel Resources Techniques Technology Training Universities clinical diagnostics design drug discovery drug metabolism exosome fabrication genome sequencing interest laboratory development manufacturing technology nano nanofabrication nanofluidic nanoscale novel organ on a chip outreach

项目摘要

PROJECT SUMMARY – CORE D Over the past twenty-five years, there has been tremendous growth in the development of lab-on-a-chip technologies for clinical, environmental and biological applications. These devices are constructed using fabrication technologies that were originally developed to produce integrated circuits. Similar to integrated circuits, these devices can integrate several different bioanalytical processes into a single platform only a few centimeters in size. Microfluidics have been used for many applications in biomedical research, from analyzing the contents of single cells to mimicking the complex environments of human organs to better understand cell- cell interactions. The KU Nanofabrication Facility is a Core Laboratory supported by the COBRE Center for Molecular Analysis of Disease Pathways at the University of Kansas. It provides the resources and personnel for the production of micro- and nanoscale devices that are used by project investigators for their studies. Equipment and training are available to investigators for the fabrication of devices for biomedical, biophysical, and bioanalytical studies related to disease pathways. The goals of KUNF in Phase 3 are (1) to develop and maintain a Core infrastructure that allows the efficient design and fabrication of nano- and microscale devices for use by project investigators and researchers from the University of Kansas, other regional universities, and private institutions for biomedical research, (2) to provide outreach, training and assistance in the development of nano- and microfluidic devices for the investigation of disease pathways, (3) to provide access to and assistance with the development of nano- and microfluidic devices and to fabricate custom devices for investigators, and (4) to continue developing a critical mass of Core Lab users, so that the facility becomes a self-sustaining, integral part of the biomedical research infrastructure in the state of Kansas and the surrounding region.

项目摘要 – 核心 D 在过去的二十五年里，芯片实验室的发展取得了巨大的进步这些设备是使用用于临床、环境和生物应用的技术构建的。最初开发用于生产集成电路的制造技术。电路，这些设备可以将几种不同的生物分析过程集成到一个平台中，只需几个尺寸为厘米的微流体已在生物医学研究中得到广泛应用。单细胞的内容来模拟人体器官的复杂环境，以更好地了解细胞 KU 纳米制造设施是 COBRE 中心支持的核心实验室。堪萨斯大学疾病途径分子分析提供资源和人员。用于生产项目研究人员用于研究的微米级和纳米级设备。研究人员可以使用设备和培训来制造生物医学、生物物理、以及与疾病途径相关的生物分析研究。 KUNF 在第 3 阶段的目标是 (1) 开发和维护核心基础设施，以实现高效的设计和制造纳米和微米级设备，供项目研究人员和研究人员使用堪萨斯大学、其他地区大学和私人生物医学研究机构，(2) 为纳米和微流体设备的开发提供外展、培训和援助疾病途径的调查，(3) 提供纳米和纳米技术的开发并提供帮助微流体设备并为研究人员制造定制设备，以及（4）继续开发关键的大量核心实验室用户，使该设施成为生物医学研究的自我维持、不可或缺的一部分堪萨斯州及周边地区的基础设施。