CRC FOR THE STUDY OF SCHIZOPHRENIA & PSYCHIATRIC REHAB.

CRC 用于精神分裂症研究

• 批准号: 2839169
• 负责人: ROBERT P LIBERMAN
• 金额: $ 168.49万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 1977
• 资助国家: 美国
• 起止时间: 1977-09-29 至 2000-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2839169
• 关键词: biomedical facility; clinical research; schizophrenia

The CRC for Schizophrenia is a multidisciplinary organization of scientists conducting research and development of diagnostic, assessment and treatment methods and providing core research services to independently funded projects comprising psychobiological studies of etiology, course and outcome and biobehavioral treatment effects on schizophrenia and other serious mental disorders. A heuristic vulnerability-stress-protective factors conceptual framework of schizophrenia guides hypothesis-driven research and, in return, is informed by project findings. Longitudinal studies are multidimensional in determining the interplay of genetic, developmental, neurocognitive, socio-behavioral, family, and psychophysiological factors on psychopathology and psychosocial functioning. The CRC consists of core labs that provide direct and consultative research services to integral and affiliated projects in areas of diagnosis/psychopathology, family processes, cognition/psychophysiology/neuropsychology, behavioral assessment and social skills, psychopharmacology, and methodology and statistics. Core labs also conduct research and development on instrumentation and pilot studies in promising areas, resulting in applications for independent, extramural support for new projects. Priority in the CRC is given to the development and validation of innovative and integrated drug and psychosocial treatment and rehabilitation interventions that are designed from knowledge gained through studies that identify predictors and correlates of course and outcome of schizophrenic disorders. Research is conducted with quality assurance procedures that maintain rigorous, reliable, and ethical pursuit of data through Center-wide, criterion-based training of assessors, audits, peer consultation, and monitoring. Research training is carried out with pre-and postdoctoral and visiting clinical research fellows through apprenticeships with CRC faculty. In the past five years, more than 50 fellows received training at the CRC, many of them continuing to collaborate with the CRC after launching their research careers elsewhere. Cross-validation, replication and dissemination of research methods and novel treatments is accomplished through collaborative studies with other investigators throughout the USA and the world. Adaptation and utilization of CRC findings are promoted among mental health clinicians through workshops, publications, manuals, and video-assisted treatment modules to bridge the gap between research and practice.

CRC 精神分裂症是一个多学科组织 科学家进行诊断、评估的研究和开发 和治疗方法并提供核心研究服务 独立资助的项目，包括心理生物学研究 病因、病程和结果以及生物行为治疗的影响 精神分裂症和其他严重的精神障碍。 启发式 脆弱性-压力-保护因素概念框架 精神分裂症指导假设驱动的研究，作为回报， 根据项目调查结果提供信息。 纵向研究是多维的 确定遗传、发育、神经认知的相互作用， 社会行为、家庭和心理生理因素 精神病理学和心理社会功能。 CRC 由核心实验室组成，提供直接和咨询服务 为以下领域的整体和附属项目提供研究服务 诊断/精神病理学、家庭过程、 认知/心理生理学/神经心理学、行为评估和 社交技能、精神药理学、方法论和统计学。 核 实验室还进行仪器和试点的研究和开发 在有前途的领域进行研究，从而产生独立的申请， 对新项目的外部支持。 CRC 的优先事项是开发和验证 创新和综合的药物和心理社会治疗以及 根据所获得的知识设计的康复干预措施 通过研究确定预测因素和相关性 精神分裂症的结果。 研究是高质量进行的 保持严格、可靠和道德的保证程序 通过在中心范围内基于标准的培训来追求数据 评估员、审计、同行咨询和监督。 对博士前、博士后和访问学者进行研究培训 通过 CRC 教师的学徒期成为临床研究员。 在 过去五年，超过50名研究员在CRC接受培训， 他们中的许多人在推出其产品后继续与 CRC 合作 其他地方的研究职业。 交叉验证、复制和 完成研究方法和新疗法的传播 通过与美国各地其他研究人员的合作研究 和世界。 促进 CRC 研究结果的适应和利用 通过讲习班、出版物、手册、 和视频辅助治疗模块，以缩小研究之间的差距 并练习。